Purpose - This chapter provides one aspect of the organizational side of the biology and politics enterprise. Design/methodology/approach - This chapter provides a historical description of two organizations that help to structure the ''business'' of biology and politics: The International Political Science Association's (IPSA) Research Committee #12 and the Association for Politics and the Life Sciences (APLS). Findings - Research Committee #12 had its origins in the early 1970s, whereas APLS came about in the later 1970s. The discussion of these two organizations gives the reader a better sense of the twin enterprises. In the process of discussing APLS, the chapter also outlines the contributions of its professional journal, Politics and the Life Sciences. Originality/value - Seldom has there been a detailed discussion of these two organizations in one place.