Bioreactors for tissue engineering purposes

Kory Blose, Jeffrey T. Krawiec, Justin S. Weinbaum, David A. Vorp

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

Bioreactors are a tool used in tissue engineering to mature and guide the development of tissue engineered constructs. Bioreactors are in vitro culture systems that have been designed to alter the following basic physiological phenomena: cell survival along with tissue structure, organization, mechanical properties, and function. Bioreactors ensure cell survival through adequate delivery of essential nutrients throughout the three-dimensional tissue engineered construct. Bioreactors can also guide tissue structure, organization, and ultimately function through the application of chemical and mechanical stimuli. It is important to understand the proper implementation of bioreactor design principles in order to create better tissue engineered products like artificial organs for transplantation. The purpose of this chapter is to illustrate these general principles using the vascular tissue engineering paradigm.

Original languageEnglish (US)
Title of host publicationRegenerative Medicine Applications in Organ Transplantation
PublisherElsevier Inc.
Pages177-185
Number of pages9
ISBN (Print)9780123985231
DOIs
StatePublished - Jan 1 2014

Fingerprint

Bioreactors
Tissue Engineering
Tissue engineering
Tissue
Cell Survival
Cells
Artificial Organs
Physiological Phenomena
Artificial organs
Organ Transplantation
Nutrients
Blood Vessels
Food
Mechanical properties

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Blose, K., Krawiec, J. T., Weinbaum, J. S., & Vorp, D. A. (2014). Bioreactors for tissue engineering purposes. In Regenerative Medicine Applications in Organ Transplantation (pp. 177-185). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-398523-1.00013-6
Blose, Kory ; Krawiec, Jeffrey T. ; Weinbaum, Justin S. ; Vorp, David A. / Bioreactors for tissue engineering purposes. Regenerative Medicine Applications in Organ Transplantation. Elsevier Inc., 2014. pp. 177-185
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Blose, K, Krawiec, JT, Weinbaum, JS & Vorp, DA 2014, Bioreactors for tissue engineering purposes. in Regenerative Medicine Applications in Organ Transplantation. Elsevier Inc., pp. 177-185. https://doi.org/10.1016/B978-0-12-398523-1.00013-6

Bioreactors for tissue engineering purposes. / Blose, Kory; Krawiec, Jeffrey T.; Weinbaum, Justin S.; Vorp, David A.

Regenerative Medicine Applications in Organ Transplantation. Elsevier Inc., 2014. p. 177-185.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Blose K, Krawiec JT, Weinbaum JS, Vorp DA. Bioreactors for tissue engineering purposes. In Regenerative Medicine Applications in Organ Transplantation. Elsevier Inc. 2014. p. 177-185 https://doi.org/10.1016/B978-0-12-398523-1.00013-6