Bispectral index monitoring in the management of sedation in an intensive care unit patient with locked-in syndrome

Sadeq A. Quraishi, Sandralee A. Blosser, Robert A. Cherry

Research output: Contribution to journalArticle

1 Scopus citations


Locked-in syndrome is an extremely rare neurological state caused by injury of the ventral pons. The syndrome is characterized by quadriplegia and anarthria with concomitant preservation of cortical function. When a reversible underlying pathological abnormality is identified and managed aggressively, meaningful recovery is possible. Because patients retain consciousness through -out their illness, a dependable method for titrating sedation may improve their quality of life. The case presented suggests that bispectral index monitoring may be a cost-effective and reliable method for managing sedation in patients with locked-in syndrome.

Original languageEnglish (US)
Pages (from-to)487-490
Number of pages4
JournalAmerican Journal of Critical Care
Issue number6
Publication statusPublished - Nov 1 2011


All Science Journal Classification (ASJC) codes

  • Critical Care

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