Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements

Sahin Kaya Ozdemir, Sotetsu Takamiya, Satoshi Ito, Shigenobu Shinohara, Hirofumi Yoshida

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Recently, we demonstrated that the speckle signal from a self-mixing laser diode (SM-LD) can be used for non-invasive measurements of relative blood flow in the human body. The measurement of blood flow is based on counting the number of the intensity changes in the speckle signal of an SM-LD in a predetermined time interval and calculating the mean speckle frequency. It was shown by performing measurements on healthy human volunteers that the mean speckle frequency is higher in the areas where blood flow is active (e.g. enhanced flow, along observable vessels, healthy scabs) but has smaller values on the areas where blood flow is not active or restricted (e.g. areas with non-observable vessels). The blood flow velocity obtained on those measurements is a relative value but it has consistent linear relation characteristics with the mean flow velocity. In this paper, we study the effect of background reflectance and hematocrit level of the blood on the mean speckle frequency by a simple model. On the basis of the results, we discuss the possibility of calibrating the measurements to get an idea on the absolute velocity measurements.

Original languageEnglish (US)
Title of host publicationCLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1008-1009
Number of pages2
ISBN (Electronic)0780356616, 9780780356610
DOIs
StatePublished - Jan 1 1999
Event1999 Pacific Rim Conference on Lasers and Electro-Optics, CLEO/Pacific Rim 1999 - Seoul, Korea, Republic of
Duration: Aug 30 1999Sep 3 1999

Publication series

NameCLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics
Volume3

Other

Other1999 Pacific Rim Conference on Lasers and Electro-Optics, CLEO/Pacific Rim 1999
CountryKorea, Republic of
CitySeoul
Period8/30/999/3/99

Fingerprint

hematocrit
flow measurement
Flow measurement
blood flow
Semiconductor lasers
Speckle
Blood
semiconductor lasers
reflectance
vessels
Flow velocity
flow velocity
human body
calibrating
velocity measurement
blood
counting
Velocity measurement
intervals

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Computer Networks and Communications
  • Physics and Astronomy(all)

Cite this

Ozdemir, S. K., Takamiya, S., Ito, S., Shinohara, S., & Yoshida, H. (1999). Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements. In CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics (pp. 1008-1009). [817945] (CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics; Vol. 3). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CLEOPR.1999.817945
Ozdemir, Sahin Kaya ; Takamiya, Sotetsu ; Ito, Satoshi ; Shinohara, Shigenobu ; Yoshida, Hirofumi. / Blood Flow measurements using self-mixing laser diode : Effect of hematocrit level and background reflectance on measuerements. CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics. Institute of Electrical and Electronics Engineers Inc., 1999. pp. 1008-1009 (CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics).
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abstract = "Recently, we demonstrated that the speckle signal from a self-mixing laser diode (SM-LD) can be used for non-invasive measurements of relative blood flow in the human body. The measurement of blood flow is based on counting the number of the intensity changes in the speckle signal of an SM-LD in a predetermined time interval and calculating the mean speckle frequency. It was shown by performing measurements on healthy human volunteers that the mean speckle frequency is higher in the areas where blood flow is active (e.g. enhanced flow, along observable vessels, healthy scabs) but has smaller values on the areas where blood flow is not active or restricted (e.g. areas with non-observable vessels). The blood flow velocity obtained on those measurements is a relative value but it has consistent linear relation characteristics with the mean flow velocity. In this paper, we study the effect of background reflectance and hematocrit level of the blood on the mean speckle frequency by a simple model. On the basis of the results, we discuss the possibility of calibrating the measurements to get an idea on the absolute velocity measurements.",
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Ozdemir, SK, Takamiya, S, Ito, S, Shinohara, S & Yoshida, H 1999, Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements. in CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics., 817945, CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics, vol. 3, Institute of Electrical and Electronics Engineers Inc., pp. 1008-1009, 1999 Pacific Rim Conference on Lasers and Electro-Optics, CLEO/Pacific Rim 1999, Seoul, Korea, Republic of, 8/30/99. https://doi.org/10.1109/CLEOPR.1999.817945

Blood Flow measurements using self-mixing laser diode : Effect of hematocrit level and background reflectance on measuerements. / Ozdemir, Sahin Kaya; Takamiya, Sotetsu; Ito, Satoshi; Shinohara, Shigenobu; Yoshida, Hirofumi.

CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics. Institute of Electrical and Electronics Engineers Inc., 1999. p. 1008-1009 817945 (CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics; Vol. 3).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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N2 - Recently, we demonstrated that the speckle signal from a self-mixing laser diode (SM-LD) can be used for non-invasive measurements of relative blood flow in the human body. The measurement of blood flow is based on counting the number of the intensity changes in the speckle signal of an SM-LD in a predetermined time interval and calculating the mean speckle frequency. It was shown by performing measurements on healthy human volunteers that the mean speckle frequency is higher in the areas where blood flow is active (e.g. enhanced flow, along observable vessels, healthy scabs) but has smaller values on the areas where blood flow is not active or restricted (e.g. areas with non-observable vessels). The blood flow velocity obtained on those measurements is a relative value but it has consistent linear relation characteristics with the mean flow velocity. In this paper, we study the effect of background reflectance and hematocrit level of the blood on the mean speckle frequency by a simple model. On the basis of the results, we discuss the possibility of calibrating the measurements to get an idea on the absolute velocity measurements.

AB - Recently, we demonstrated that the speckle signal from a self-mixing laser diode (SM-LD) can be used for non-invasive measurements of relative blood flow in the human body. The measurement of blood flow is based on counting the number of the intensity changes in the speckle signal of an SM-LD in a predetermined time interval and calculating the mean speckle frequency. It was shown by performing measurements on healthy human volunteers that the mean speckle frequency is higher in the areas where blood flow is active (e.g. enhanced flow, along observable vessels, healthy scabs) but has smaller values on the areas where blood flow is not active or restricted (e.g. areas with non-observable vessels). The blood flow velocity obtained on those measurements is a relative value but it has consistent linear relation characteristics with the mean flow velocity. In this paper, we study the effect of background reflectance and hematocrit level of the blood on the mean speckle frequency by a simple model. On the basis of the results, we discuss the possibility of calibrating the measurements to get an idea on the absolute velocity measurements.

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Ozdemir SK, Takamiya S, Ito S, Shinohara S, Yoshida H. Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements. In CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics. Institute of Electrical and Electronics Engineers Inc. 1999. p. 1008-1009. 817945. (CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics). https://doi.org/10.1109/CLEOPR.1999.817945