Body fluid changes, thirst and drinking in man during free access to water

Paddy A. Phillips, Barbara Jean Rolls, John G.G. Ledingham, James J. Morton

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

To investigate whether human thirst and drinking during ad lib access to water occur in response to body fluid deficits, we obtained blood samples and visual analog scale thirst ratings from five healthy, volunteer, young men at hourly intervals and when they were thristy during a normal working day. Although there were significant increases in ratings of thirst, pleasantness of drinking water, mouth dryness and unpleasantness of the taste in the mouth when subjects were thirsty enough to drink compared with intervening intervals, there were no concomitant changes in body fluid variables (microhematocrit, plasma osmolality and plasma sodium, potassium, protein and angiotensin II concentrations). Subjects drank mainly in association with eating and were not overhydrated as indicated by constantly hypertonic urine and significant tubular reabsorption of free water over the experimental period. The results indicate that during free access to water humans become thirsty and drink before body fluid deficits develop, perhaps in response to subtle oropharyngeal cues, and so provide evidence for anticipatory thirst and drinking in man.

Original languageEnglish (US)
Pages (from-to)357-363
Number of pages7
JournalPhysiology and Behavior
Volume33
Issue number3
DOIs
StatePublished - Jan 1 1984

Fingerprint

Thirst
Body Fluids
Drinking
Water
Xerostomia
Visual Analog Scale
Angiotensin II
Drinking Water
Osmolar Concentration
Cues
Mouth
Healthy Volunteers
Potassium
Eating
Sodium
Urine
Proteins

All Science Journal Classification (ASJC) codes

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

Cite this

Phillips, Paddy A. ; Rolls, Barbara Jean ; Ledingham, John G.G. ; Morton, James J. / Body fluid changes, thirst and drinking in man during free access to water. In: Physiology and Behavior. 1984 ; Vol. 33, No. 3. pp. 357-363.
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Body fluid changes, thirst and drinking in man during free access to water. / Phillips, Paddy A.; Rolls, Barbara Jean; Ledingham, John G.G.; Morton, James J.

In: Physiology and Behavior, Vol. 33, No. 3, 01.01.1984, p. 357-363.

Research output: Contribution to journalArticle

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