Body temperature control circuit

Admir Horta; Eric Gernux; Matt Couceiro; Dieter Haemmerich; Mohamed Almekkawy

doi:10.1109/UEMCON.2016.7777815

Body temperature control circuit

Admir Horta, Eric Gernux, Matt Couceiro, Dieter Haemmerich, Mohamed Almekkawy

Computer Science and Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

There is currently no animal model available that allows chronic control of body temperature, e.g. to study the effects of body temperature on disease. Prior studies have shown that by heating the preoptic area (POA) of the hypothalamus of rodents with a heated water-perfused probe the body temperature can be lowered, but this method is not feasible for chronic use. Here we present two control circuit designs that employ high performance operational amplifiers and a feedback network that has the ability to chronically modulate the temperature of the POA of the hypothalamus, thus adjusting the body temperature set point. This will be done by permanently implanting a heated micro-probe (thermistor) and using a feedback system to accurately control the temperature of the thermistor to help the brain center control the temperature. The control circuit and feedback network were designed to provide accurate and sustainable control over the subjects body temperature while focusing on the miniaturization of components without sacrificing performance. For this design the power consumed by the circuit was achieved to be 3.8 mW and the size of the board is currently 9 cm². Tadiran batteries were used to employ high-performance button cells. The thermistor used is around 360 μm and it is capable of controlling the temperature between 98.6 °F/37 °C and 122 °F/50 °C. Thus, the circuit is sufficiently small to be carried by a rodent while chronically controlling the POA temperature.

Original language	English (US)
Title of host publication	2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016
Editors	Himadri Nath Saha, Satyajit Chakrabarti
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781509014965
DOIs	https://doi.org/10.1109/UEMCON.2016.7777815
State	Published - Dec 7 2016
Event	7th IEEE Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016 - New York City, United States Duration: Oct 20 2016 → Oct 22 2016

Publication series

Name	2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016

Other

Other	7th IEEE Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016
Country/Territory	United States
City	New York City
Period	10/20/16 → 10/22/16

All Science Journal Classification (ASJC) codes

Hardware and Architecture
Artificial Intelligence
Computer Networks and Communications
Computer Science Applications
Electrical and Electronic Engineering

Access to Document

10.1109/UEMCON.2016.7777815

Cite this

Horta, A., Gernux, E., Couceiro, M., Haemmerich, D., & Almekkawy, M. (2016). Body temperature control circuit. In H. N. Saha, & S. Chakrabarti (Eds.), 2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016 [7777815] (2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/UEMCON.2016.7777815

Horta, Admir ; Gernux, Eric ; Couceiro, Matt et al. / Body temperature control circuit. 2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016. editor / Himadri Nath Saha ; Satyajit Chakrabarti. Institute of Electrical and Electronics Engineers Inc., 2016. (2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016).

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title = "Body temperature control circuit",

abstract = "There is currently no animal model available that allows chronic control of body temperature, e.g. to study the effects of body temperature on disease. Prior studies have shown that by heating the preoptic area (POA) of the hypothalamus of rodents with a heated water-perfused probe the body temperature can be lowered, but this method is not feasible for chronic use. Here we present two control circuit designs that employ high performance operational amplifiers and a feedback network that has the ability to chronically modulate the temperature of the POA of the hypothalamus, thus adjusting the body temperature set point. This will be done by permanently implanting a heated micro-probe (thermistor) and using a feedback system to accurately control the temperature of the thermistor to help the brain center control the temperature. The control circuit and feedback network were designed to provide accurate and sustainable control over the subjects body temperature while focusing on the miniaturization of components without sacrificing performance. For this design the power consumed by the circuit was achieved to be 3.8 mW and the size of the board is currently 9 cm2. Tadiran batteries were used to employ high-performance button cells. The thermistor used is around 360 μm and it is capable of controlling the temperature between 98.6 °F/37 °C and 122 °F/50 °C. Thus, the circuit is sufficiently small to be carried by a rodent while chronically controlling the POA temperature.",

author = "Admir Horta and Eric Gernux and Matt Couceiro and Dieter Haemmerich and Mohamed Almekkawy",

year = "2016",

month = dec,

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doi = "10.1109/UEMCON.2016.7777815",

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series = "2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016",

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booktitle = "2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016",

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note = "7th IEEE Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016 ; Conference date: 20-10-2016 Through 22-10-2016",

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Horta, A, Gernux, E, Couceiro, M, Haemmerich, D & Almekkawy, M 2016, Body temperature control circuit. in HN Saha & S Chakrabarti (eds), 2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016., 7777815, 2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016, Institute of Electrical and Electronics Engineers Inc., 7th IEEE Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016, New York City, United States, 10/20/16. https://doi.org/10.1109/UEMCON.2016.7777815

Body temperature control circuit. / Horta, Admir; Gernux, Eric; Couceiro, Matt et al.
2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016. ed. / Himadri Nath Saha; Satyajit Chakrabarti. Institute of Electrical and Electronics Engineers Inc., 2016. 7777815 (2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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Horta A, Gernux E, Couceiro M, Haemmerich D, Almekkawy M. Body temperature control circuit. In Saha HN, Chakrabarti S, editors, 2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016. Institute of Electrical and Electronics Engineers Inc. 2016. 7777815. (2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016). doi: 10.1109/UEMCON.2016.7777815

Body temperature control circuit

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