Body temperature control circuit

Admir Horta, Eric Gernux, Matt Couceiro, Dieter Haemmerich, Mohamed Almekkawy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

There is currently no animal model available that allows chronic control of body temperature, e.g. to study the effects of body temperature on disease. Prior studies have shown that by heating the preoptic area (POA) of the hypothalamus of rodents with a heated water-perfused probe the body temperature can be lowered, but this method is not feasible for chronic use. Here we present two control circuit designs that employ high performance operational amplifiers and a feedback network that has the ability to chronically modulate the temperature of the POA of the hypothalamus, thus adjusting the body temperature set point. This will be done by permanently implanting a heated micro-probe (thermistor) and using a feedback system to accurately control the temperature of the thermistor to help the brain center control the temperature. The control circuit and feedback network were designed to provide accurate and sustainable control over the subjects body temperature while focusing on the miniaturization of components without sacrificing performance. For this design the power consumed by the circuit was achieved to be 3.8 mW and the size of the board is currently 9 cm2. Tadiran batteries were used to employ high-performance button cells. The thermistor used is around 360 μm and it is capable of controlling the temperature between 98.6 °F/37 °C and 122 °F/50 °C. Thus, the circuit is sufficiently small to be carried by a rodent while chronically controlling the POA temperature.

Original languageEnglish (US)
Title of host publication2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016
EditorsHimadri Nath Saha, Satyajit Chakrabarti
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781509014965
DOIs
StatePublished - Dec 7 2016
Event7th IEEE Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016 - New York City, United States
Duration: Oct 20 2016Oct 22 2016

Publication series

Name2016 IEEE 7th Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016

Other

Other7th IEEE Annual Ubiquitous Computing, Electronics and Mobile Communication Conference, UEMCON 2016
CountryUnited States
CityNew York City
Period10/20/1610/22/16

All Science Journal Classification (ASJC) codes

  • Hardware and Architecture
  • Artificial Intelligence
  • Computer Networks and Communications
  • Computer Science Applications
  • Electrical and Electronic Engineering

Fingerprint Dive into the research topics of 'Body temperature control circuit'. Together they form a unique fingerprint.

Cite this