Brominated flame retardants in serum from U.S. blood donors

Andreas Sjödin, Donald George Jr Patterson, Åke Bergman

Research output: Contribution to journalArticle

129 Citations (Scopus)

Abstract

Serum samples collected in 1988 from U.S. blood donors were analyzed for polybrominated diphenyl ethers (PBDEs) and polychlorinated and polybrominated biphenyls (PCBs and PBBs). The levels of the PBDEs are reported for the first time in serum from the U.S. population. The median concentrations and range of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47); 2,2′,4,4′,5,5′-hexabromodiphenyl ether (BDE-153); 2,2′,3,4,4′,5′,6-heptabromodiphenyl ether (BDE-183); and decabromodiphenyl ether (BDE-209) were 1.3 (>0.8-49); 0.54 (0.13-3.1); 0.24 (0.12-1.8); and >1 (>1-35) pmol/g lipid weight (l.w.), respectively. In addition we also measured detectable levels of nine additional PBDE congeners in many of the serum samples. The median concentrations and ranges of 2,2′,4,4′,5,5′-hexachloro- and hexabromobiphenyl (CB-153 and BB-153) were 190 (21-2600) and 19 (4.2-84) pmol/g l.w. The levels of PBDEs and CB-153 found in the U.S. samples were similar to background levels reported in the serum of Swedish hospital cleaners collected 10 years later, i.e., 1997. The BB-153 congener measured in the U.S. samples was not found in the Swedish samples. The difference in exposure to this congener could not be assessed in this study, although might be related to the 1973 BB-153 (FireMaster BP-6) animal and human contamination incident in the State of Michigan.

Original languageEnglish (US)
Pages (from-to)3830-3833
Number of pages4
JournalEnvironmental Science and Technology
Volume35
Issue number19
DOIs
StatePublished - Oct 1 2001

Fingerprint

2,4,5,2',4',5'-hexachlorobiphenyl
Halogenated Diphenyl Ethers
Flame Retardants
decabromobiphenyl ether
PBDE
ether
serum
Blood
blood
Polychlorinated Biphenyls
Ether
PCB
Polybrominated Biphenyls
lipid
Lipids
background level
Animals
Contamination
flame retardant
animal

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Environmental Chemistry

Cite this

Sjödin, Andreas ; Patterson, Donald George Jr ; Bergman, Åke. / Brominated flame retardants in serum from U.S. blood donors. In: Environmental Science and Technology. 2001 ; Vol. 35, No. 19. pp. 3830-3833.
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abstract = "Serum samples collected in 1988 from U.S. blood donors were analyzed for polybrominated diphenyl ethers (PBDEs) and polychlorinated and polybrominated biphenyls (PCBs and PBBs). The levels of the PBDEs are reported for the first time in serum from the U.S. population. The median concentrations and range of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47); 2,2′,4,4′,5,5′-hexabromodiphenyl ether (BDE-153); 2,2′,3,4,4′,5′,6-heptabromodiphenyl ether (BDE-183); and decabromodiphenyl ether (BDE-209) were 1.3 (>0.8-49); 0.54 (0.13-3.1); 0.24 (0.12-1.8); and >1 (>1-35) pmol/g lipid weight (l.w.), respectively. In addition we also measured detectable levels of nine additional PBDE congeners in many of the serum samples. The median concentrations and ranges of 2,2′,4,4′,5,5′-hexachloro- and hexabromobiphenyl (CB-153 and BB-153) were 190 (21-2600) and 19 (4.2-84) pmol/g l.w. The levels of PBDEs and CB-153 found in the U.S. samples were similar to background levels reported in the serum of Swedish hospital cleaners collected 10 years later, i.e., 1997. The BB-153 congener measured in the U.S. samples was not found in the Swedish samples. The difference in exposure to this congener could not be assessed in this study, although might be related to the 1973 BB-153 (FireMaster BP-6) animal and human contamination incident in the State of Michigan.",
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Brominated flame retardants in serum from U.S. blood donors. / Sjödin, Andreas; Patterson, Donald George Jr; Bergman, Åke.

In: Environmental Science and Technology, Vol. 35, No. 19, 01.10.2001, p. 3830-3833.

Research output: Contribution to journalArticle

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