Bronchopneumonia associated with extraintestinal pathogenic Escherichia coli in a horse

Chitrita DebRoy, Elisabeth Roberts, Bhushan M. Jayarao, Jason W. Brooks

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Extraintestinal pathogenic Escherichia coli (ExPEC) strains carrying distinct virulence attributes are known to cause diseases in humans and animals and infect organs other than the gastrointestinal tract. A fatal case of bronchopneumonia in a 12-year-old female Quarterhorse was investigated. Following postmortem examination, E coli, Enterococcus sp., and Klebsiella pneumonia were isolated from the lungs, which contained multifocal intra-alveolar accumulations of neutrophils and macrophages with edema, hemorrhage, and fibrin. The strain of E. coli belonged to O2:H21 and carried virulence genes cnf1, sfa, foe, fimA, and papG allele I that are known to be associated with ExPEC strains. The strain was resistant to several antimicrobials including clindamycin, erythromycin, oxacillin, penicillin, and rifampin. This is the first report, to the authors' knowledge, in which ExPEC O2:H21 has been associated with fatal bronchopneumonia in a horse.

Original languageEnglish (US)
Pages (from-to)661-664
Number of pages4
JournalJournal of Veterinary Diagnostic Investigation
Volume20
Issue number5
DOIs
StatePublished - Sep 1 2008

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Bronchopneumonia
bronchopneumonia
Horses
Escherichia coli
horses
Virulence
Animal Structures
Oxacillin
Clindamycin
Enterococcus
Klebsiella pneumoniae
Erythromycin
Rifampin
Fibrin
Penicillins
virulence
Gastrointestinal Tract
Autopsy
Edema
Neutrophils

All Science Journal Classification (ASJC) codes

  • veterinary(all)

Cite this

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Bronchopneumonia associated with extraintestinal pathogenic Escherichia coli in a horse. / DebRoy, Chitrita; Roberts, Elisabeth; Jayarao, Bhushan M.; Brooks, Jason W.

In: Journal of Veterinary Diagnostic Investigation, Vol. 20, No. 5, 01.09.2008, p. 661-664.

Research output: Contribution to journalArticle

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