Bulk Mass Transport Limitations during High‐Flux Hemodialysis

Research output: Contribution to journalEditorial

24 Citations (Scopus)

Abstract

Abstract: Solute clearance during high‐flux hemodialysis is determined by the combined effects of solute convection and diffusion in the membrane, blood, and dialysate. Previous studies have focused almost entirely on the membrane transport phenomena, largely ignoring the potential contribution from bulk mass transport across the fluid boundary layers in the blood and dialysate. This study presents a theoretical analysis of the coupled transport equations in the membrane, blood, and dialysate including the contributions from both convective and diffusive transport in each of these regions. The resulting theoretical expression for the solute flux demonstrates that bulk mass transfer limitations can have an important effect on solute transport and, in turn, solute clearance during high‐flux hemodialysis.

Original languageEnglish (US)
Pages (from-to)919-924
Number of pages6
JournalArtificial organs
Volume17
Issue number11
DOIs
StatePublished - Jan 1 1993

Fingerprint

Dialysis Solutions
Renal Dialysis
Blood
Mass transfer
Membranes
Solute transport
Convection
Boundary layers
Fluxes
Fluids

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

Cite this

@article{45f94f5e8937426ebb3b1992090a5315,
title = "Bulk Mass Transport Limitations during High‐Flux Hemodialysis",
abstract = "Abstract: Solute clearance during high‐flux hemodialysis is determined by the combined effects of solute convection and diffusion in the membrane, blood, and dialysate. Previous studies have focused almost entirely on the membrane transport phenomena, largely ignoring the potential contribution from bulk mass transport across the fluid boundary layers in the blood and dialysate. This study presents a theoretical analysis of the coupled transport equations in the membrane, blood, and dialysate including the contributions from both convective and diffusive transport in each of these regions. The resulting theoretical expression for the solute flux demonstrates that bulk mass transfer limitations can have an important effect on solute transport and, in turn, solute clearance during high‐flux hemodialysis.",
author = "Andrew Zydney",
year = "1993",
month = "1",
day = "1",
doi = "10.1111/j.1525-1594.1993.tb00403.x",
language = "English (US)",
volume = "17",
pages = "919--924",
journal = "Artificial Organs",
issn = "0160-564X",
publisher = "Wiley-Blackwell",
number = "11",

}

Bulk Mass Transport Limitations during High‐Flux Hemodialysis. / Zydney, Andrew.

In: Artificial organs, Vol. 17, No. 11, 01.01.1993, p. 919-924.

Research output: Contribution to journalEditorial

TY - JOUR

T1 - Bulk Mass Transport Limitations during High‐Flux Hemodialysis

AU - Zydney, Andrew

PY - 1993/1/1

Y1 - 1993/1/1

N2 - Abstract: Solute clearance during high‐flux hemodialysis is determined by the combined effects of solute convection and diffusion in the membrane, blood, and dialysate. Previous studies have focused almost entirely on the membrane transport phenomena, largely ignoring the potential contribution from bulk mass transport across the fluid boundary layers in the blood and dialysate. This study presents a theoretical analysis of the coupled transport equations in the membrane, blood, and dialysate including the contributions from both convective and diffusive transport in each of these regions. The resulting theoretical expression for the solute flux demonstrates that bulk mass transfer limitations can have an important effect on solute transport and, in turn, solute clearance during high‐flux hemodialysis.

AB - Abstract: Solute clearance during high‐flux hemodialysis is determined by the combined effects of solute convection and diffusion in the membrane, blood, and dialysate. Previous studies have focused almost entirely on the membrane transport phenomena, largely ignoring the potential contribution from bulk mass transport across the fluid boundary layers in the blood and dialysate. This study presents a theoretical analysis of the coupled transport equations in the membrane, blood, and dialysate including the contributions from both convective and diffusive transport in each of these regions. The resulting theoretical expression for the solute flux demonstrates that bulk mass transfer limitations can have an important effect on solute transport and, in turn, solute clearance during high‐flux hemodialysis.

UR - http://www.scopus.com/inward/record.url?scp=0027453650&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027453650&partnerID=8YFLogxK

U2 - 10.1111/j.1525-1594.1993.tb00403.x

DO - 10.1111/j.1525-1594.1993.tb00403.x

M3 - Editorial

C2 - 8110060

AN - SCOPUS:0027453650

VL - 17

SP - 919

EP - 924

JO - Artificial Organs

JF - Artificial Organs

SN - 0160-564X

IS - 11

ER -