Burden of Uncontrolled Hyperglycemia and Its Association with Patients Characteristics and Socioeconomic Status in Philadelphia, USA

Longjian Liu, Fengge Wang, Edward J. Gracely, Kari Moore, Steven Melly, Fengqing Zhang, Priscila Y. Sato, Howard J. Eisen

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To examine the burden of uncontrolled hyperglycemia in patients with diabetes mellitus (DM) and their characteristics in a large urban city. Methods: A randomized sample of 4993 patients with DM ≥18 years old who received routine health care in a large university teaching hospital in the city of Philadelphia was analyzed. Uncontrolled hyperglycemia was classified as blood hemoglobin A1c >8%. The associations of uncontrolled hyperglycemia with sociodemographic and cardiovascular factors were analyzed using univariate and multivariate analysis methods. Results: The results show that patients 18-54 years had the highest prevalence of uncontrolled hyperglycemia (36.0%), followed by those at age 55-64 (30.9%), 65-74 (22.9%), and ≥75 (20.6%) years (p<0.0001). Unadjusted hyperglycemia was significantly associated with patients with increased total cholesterol to high-density lipoprotein ratio (odds ratio [OR]=1.59, 95% confidence interval [CI]: 1.33-1.90, p<0.001), and with prevalent coronary heart disease (OR=1.39, 95% CI: 1.16-1.67, p=0.001). Patients living in neighborhoods with lower socioeconomic status (SES) had significantly higher uncontrolled hyperglycemia rates across the city (r=0.52, R2=0.27, p=0.03). Conclusions: Findings of this study is one of the first studies to address that younger adults had higher rates of uncontrolled hyperglycemia. Further attention should be paid to the challenges of controlling DM in younger adults and patients who live in neighborhoods with lower SES.

Original languageEnglish (US)
Pages (from-to)525-532
Number of pages8
JournalHealth Equity
Volume4
Issue number1
DOIs
StatePublished - Dec 1 2020

All Science Journal Classification (ASJC) codes

  • Health Policy
  • Public Health, Environmental and Occupational Health
  • Health(social science)
  • Health Information Management

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