Calcium-Blocker Therapy for Unstable Angina Pectoris

Research output: Contribution to journalEditorial

28 Citations (Scopus)

Abstract

Now that the calcium blockers are available, how does this change the modern management of angina pectoris? Although there are relatively unusual causes of angina, such as hypertrophic cardiomyopathy and aortic stenosis, the vast majority of these patients have fixed atherosclerotic coronary-artery disease, and pain occurs when myocardial oxygen requirements increase. This pathophysiologic process gives rise to the syndrome of chronic stable exertional angina. Current therapy consists of nitrates and beta-adrenergic-receptor blocking agents to decrease myocardial oxygen consumption, with coronary-bypass surgery for patients at high risk of myocardial infarction or those unresponsive to medical therapy. A few patients have a. . .

Original languageEnglish (US)
Pages (from-to)926-928
Number of pages3
JournalNew England Journal of Medicine
Volume306
Issue number15
DOIs
StatePublished - Apr 15 1982

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Unstable Angina
Calcium
Adrenergic beta-Antagonists
Stable Angina
Hypertrophic Cardiomyopathy
Receptors, Adrenergic, beta
Aortic Valve Stenosis
Angina Pectoris
Oxygen Consumption
Nitrates
Coronary Artery Disease
Therapeutics
Myocardial Infarction
Oxygen
Pain

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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abstract = "Now that the calcium blockers are available, how does this change the modern management of angina pectoris? Although there are relatively unusual causes of angina, such as hypertrophic cardiomyopathy and aortic stenosis, the vast majority of these patients have fixed atherosclerotic coronary-artery disease, and pain occurs when myocardial oxygen requirements increase. This pathophysiologic process gives rise to the syndrome of chronic stable exertional angina. Current therapy consists of nitrates and beta-adrenergic-receptor blocking agents to decrease myocardial oxygen consumption, with coronary-bypass surgery for patients at high risk of myocardial infarction or those unresponsive to medical therapy. A few patients have a. . .",
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Calcium-Blocker Therapy for Unstable Angina Pectoris. / Zelis, Robert.

In: New England Journal of Medicine, Vol. 306, No. 15, 15.04.1982, p. 926-928.

Research output: Contribution to journalEditorial

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AB - Now that the calcium blockers are available, how does this change the modern management of angina pectoris? Although there are relatively unusual causes of angina, such as hypertrophic cardiomyopathy and aortic stenosis, the vast majority of these patients have fixed atherosclerotic coronary-artery disease, and pain occurs when myocardial oxygen requirements increase. This pathophysiologic process gives rise to the syndrome of chronic stable exertional angina. Current therapy consists of nitrates and beta-adrenergic-receptor blocking agents to decrease myocardial oxygen consumption, with coronary-bypass surgery for patients at high risk of myocardial infarction or those unresponsive to medical therapy. A few patients have a. . .

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