Calcium phosphate deposition in rat kidneys

Saeed R. Khan, James Hansell Adair, Augusto A. Morrone, Guy P. Latorre

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Calcium phosphate (CaP) is a common constituent of human urinary stones. 1,2 It is suggested to be involved in crystallization of the predominant crystalline component of most urinary stones namely the calcium oxalate (CaOx). In most stones, CaP is present as apatite which occurs in two forms, hydroxylapatite and carbonate apatite. Hydroxylapatite is generally found in stones associated with sterile urine while carbonate apatite is found in stones associated with infection. To better understand the mechanisms involved in CaP deposition in mammalian kidneys and the role of CaP in crystallization of CaOx we are involved in a study of renal deposition of CaP and CaOx in Sprague-Dawley rats.

Original languageEnglish (US)
Title of host publicationHydroxyapatite and Related Materials
PublisherCRC Press
Pages325-329
Number of pages5
ISBN (Electronic)9781351439497
ISBN (Print)0849347505, 9780849347504
DOIs
StatePublished - Jan 1 2017

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All Science Journal Classification (ASJC) codes

  • Engineering(all)
  • Materials Science(all)

Cite this

Khan, S. R., Adair, J. H., Morrone, A. A., & Latorre, G. P. (2017). Calcium phosphate deposition in rat kidneys. In Hydroxyapatite and Related Materials (pp. 325-329). CRC Press. https://doi.org/10.1201/9780203751367