Calcium/calmodulin affects microtubule stability in lysed protoplasts

R. J. Cyr

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

Microtubules (Mts) are found in four distinct arrays appearing sequentially in a cell-cycle-dependent fashion within the cells of higher plants. Additionally, the cortical Mts of non cycling cells are spatially altered in a variety of differentiated states. Information regarding the molecular details underlying these Mt-reorientation events in plant cells is scarce. Moreover, it is unclear how cytoskeletal behavior integrates with the myriad of other cellular activities that are altered concomitantly in both differentiating and cycling cells. Data are presented herein to indicate that calcium, in the form of a Ca2+/ calmodulin complex, can alter the behavior of Mts in lysed carrot protoplasts. Mechanistically, we show that Ca2+/calmodulin most likely interacts with Mts via associations with microtubule associated proteins (MAPs) . These results are discussed with reference to how Ca2+ may alter the dynamic behavior of Mts during growth and development.

Original languageEnglish (US)
Pages (from-to)311-317
Number of pages7
JournalJournal of Cell Science
Volume100
Issue number2
StatePublished - Nov 18 1991

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Protoplasts
Calmodulin
Microtubules
Calcium
Plant Cells
Daucus carota
Microtubule-Associated Proteins
Growth and Development
Cell Cycle

All Science Journal Classification (ASJC) codes

  • Cell Biology

Cite this

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abstract = "Microtubules (Mts) are found in four distinct arrays appearing sequentially in a cell-cycle-dependent fashion within the cells of higher plants. Additionally, the cortical Mts of non cycling cells are spatially altered in a variety of differentiated states. Information regarding the molecular details underlying these Mt-reorientation events in plant cells is scarce. Moreover, it is unclear how cytoskeletal behavior integrates with the myriad of other cellular activities that are altered concomitantly in both differentiating and cycling cells. Data are presented herein to indicate that calcium, in the form of a Ca2+/ calmodulin complex, can alter the behavior of Mts in lysed carrot protoplasts. Mechanistically, we show that Ca2+/calmodulin most likely interacts with Mts via associations with microtubule associated proteins (MAPs) . These results are discussed with reference to how Ca2+ may alter the dynamic behavior of Mts during growth and development.",
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Calcium/calmodulin affects microtubule stability in lysed protoplasts. / Cyr, R. J.

In: Journal of Cell Science, Vol. 100, No. 2, 18.11.1991, p. 311-317.

Research output: Contribution to journalArticle

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