Can a neural circuit support multiple signal patterns?

Research output: Contribution to journalArticle

Abstract

In this study, a comprehensive cell-by-cell, synapse-by-synapse model of a living central pattern generator network was implemented in analog VLSI CMOS. In the final model, rhythms and waveforms for membrane potential in each cell were seen to compare faithfully and regularly with those of their living counterparts with nominal settings, but as key cell parameters were varied, the network assumed alternate signal patterns and rhythms. This suggests that neuromorphic structure is not enough to specify the signals that will occur in a nerve circuit. Cell parameters must be replicated as well.

Original languageEnglish (US)
Pages (from-to)1385-1386
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume3
StatePublished - 1997

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Networks (circuits)
Synapses
Membranes
Central Pattern Generators
Membrane Potentials

All Science Journal Classification (ASJC) codes

  • Bioengineering

Cite this

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title = "Can a neural circuit support multiple signal patterns?",
abstract = "In this study, a comprehensive cell-by-cell, synapse-by-synapse model of a living central pattern generator network was implemented in analog VLSI CMOS. In the final model, rhythms and waveforms for membrane potential in each cell were seen to compare faithfully and regularly with those of their living counterparts with nominal settings, but as key cell parameters were varied, the network assumed alternate signal patterns and rhythms. This suggests that neuromorphic structure is not enough to specify the signals that will occur in a nerve circuit. Cell parameters must be replicated as well.",
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