Cancer-Associated Osteoclast Differentiation Takes a Good Look in the miR(NA)ror

David L. Waning; Khalid S. Mohammad; Theresa A. Guise

doi:10.1016/j.ccr.2013.10.001

Cancer-Associated Osteoclast Differentiation Takes a Good Look in the miR(NA)ror

David L. Waning, Khalid S. Mohammad, Theresa A. Guise

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

Tumor-bone cell interactions are critical for the development of metastasis-related osteolytic bone destruction. In this issue of Cancer Cell, Ell and colleagues show how a discrete miRNA network regulates osteoclastogenesis during breast cancer bone metastasis. A signature of upregulated miRNAs may have diagnostic and therapeutic implications for bone metastases.

Original language	English (US)
Pages (from-to)	407-409
Number of pages	3
Journal	Cancer Cell
Volume	24
Issue number	4
DOIs	https://doi.org/10.1016/j.ccr.2013.10.001
State	Published - Oct 14 2013

All Science Journal Classification (ASJC) codes

Oncology
Cell Biology
Cancer Research

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@article{712e90600f064892b47cbb976f7a432a,

title = "Cancer-Associated Osteoclast Differentiation Takes a Good Look in the miR(NA)ror",

abstract = "Tumor-bone cell interactions are critical for the development of metastasis-related osteolytic bone destruction. In this issue of Cancer Cell, Ell and colleagues show how a discrete miRNA network regulates osteoclastogenesis during breast cancer bone metastasis. A signature of upregulated miRNAs may have diagnostic and therapeutic implications for bone metastases.",

author = "Waning, {David L.} and Mohammad, {Khalid S.} and Guise, {Theresa A.}",

note = "Funding Information: We acknowledge support from NIH grants (U01CA143057 from the NCI Tumor Microenvironment Network; R01CA69158), the Indiana Economic Development grant, the Jerry and Peggy Throgmartin Endowment of the IU Simon Cancer Center, and a generous donation from the Withycombe family.",

year = "2013",

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day = "14",

doi = "10.1016/j.ccr.2013.10.001",

language = "English (US)",

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journal = "Cancer Cell",

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T1 - Cancer-Associated Osteoclast Differentiation Takes a Good Look in the miR(NA)ror

AU - Waning, David L.

AU - Mohammad, Khalid S.

AU - Guise, Theresa A.

N1 - Funding Information: We acknowledge support from NIH grants (U01CA143057 from the NCI Tumor Microenvironment Network; R01CA69158), the Indiana Economic Development grant, the Jerry and Peggy Throgmartin Endowment of the IU Simon Cancer Center, and a generous donation from the Withycombe family.

PY - 2013/10/14

Y1 - 2013/10/14

N2 - Tumor-bone cell interactions are critical for the development of metastasis-related osteolytic bone destruction. In this issue of Cancer Cell, Ell and colleagues show how a discrete miRNA network regulates osteoclastogenesis during breast cancer bone metastasis. A signature of upregulated miRNAs may have diagnostic and therapeutic implications for bone metastases.

AB - Tumor-bone cell interactions are critical for the development of metastasis-related osteolytic bone destruction. In this issue of Cancer Cell, Ell and colleagues show how a discrete miRNA network regulates osteoclastogenesis during breast cancer bone metastasis. A signature of upregulated miRNAs may have diagnostic and therapeutic implications for bone metastases.

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U2 - 10.1016/j.ccr.2013.10.001

DO - 10.1016/j.ccr.2013.10.001

M3 - Short survey

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JO - Cancer Cell

JF - Cancer Cell

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