Tumor-bone cell interactions are critical for the development of metastasis-related osteolytic bone destruction. In this issue of Cancer Cell, Ell and colleagues show how a discrete miRNA network regulates osteoclastogenesis during breast cancer bone metastasis. A signature of upregulated miRNAs may have diagnostic and therapeutic implications for bone metastases.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Oct 14 2013|
All Science Journal Classification (ASJC) codes
- Cell Biology
- Cancer Research