Cancer prevention by tea and tea polyphenols

Chung S. Yang, Jihyeung Ju, Gary Lu, Hang Xiao, Xingpei Hao, Shengmin Sang, Joshua D. Lambert

Research output: Contribution to journalReview articlepeer-review

56 Scopus citations

Abstract

The inhibition of tumorigenesis by tea extracts and tea polyphenols has been demonstrated in different animal models, including those for cancer of the skin, lung, oral cavity, esophagus, stomach, small intestine, colon, bladder, liver, pancrease, prostate, and mammary glands. Caffeine is also active in inhibition of tumorigenesis on the skin, lung, and perhaps other organs. In spite of many in vitro and in vivo studies, the molecular mechanisms for the cancer preventive actions of these compounds are not clearly known. The relationship between tea consumption and cancer risk has not been conclusively demonstrated, and the relationship may become more clear if we consider the effects of specific types of tea, at defined doses, in populations with certain dietary patterns or genetic polymorphisms. Human intervention trials and large prospective studies are needed to further assess the cancer preventive activities of tea constituents.

Original languageEnglish (US)
Pages (from-to)245-248
Number of pages4
JournalAsia Pacific Journal of Clinical Nutrition
Volume17
Issue numberSUPPL. 1
StatePublished - Jan 2008

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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