TY - CHAP
T1 - Capsaicin Mediated Oxidative Stress in Pancreatic Cancer
AU - Datta, Palika
AU - Pramanik, Kartick C.
AU - Mehrotra, Sudhir
AU - Srivastava, Sanjay K.
N1 - Funding Information:
This work was supported in part by R01 grants CA129038 and CA106953 (to Sanjay K. Srivastava) awarded by The National Cancer Institute, NIH, USA.
PY - 2014/4
Y1 - 2014/4
N2 - Capsaicin, an ingredient of red chili pepper, has been shown to suppress the growth of pancreatic cancer. Its role and mechanism of action is currently under extensive investigation. Capsaicin has demonstrated the ability to inhibit the proliferation of pancreatic cancer cells through reactive oxygen species (ROS). The relationship between ROS, antioxidants, and possible pathways for inhibition of pancreatic cancer mediated by capsaicin is discussed in this chapter.
AB - Capsaicin, an ingredient of red chili pepper, has been shown to suppress the growth of pancreatic cancer. Its role and mechanism of action is currently under extensive investigation. Capsaicin has demonstrated the ability to inhibit the proliferation of pancreatic cancer cells through reactive oxygen species (ROS). The relationship between ROS, antioxidants, and possible pathways for inhibition of pancreatic cancer mediated by capsaicin is discussed in this chapter.
UR - http://www.scopus.com/inward/record.url?scp=84902072128&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84902072128&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-405205-5.00023-4
DO - 10.1016/B978-0-12-405205-5.00023-4
M3 - Chapter
AN - SCOPUS:84902072128
SN - 9780124052055
SP - 241
EP - 246
BT - Cancer
PB - Elsevier Inc.
ER -
