Carcinoid heart disease: Current understanding and future directions

Chirdeep Patel, Moses Mathur, Ricardo O. Escarcega, Alfred A. Bove

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations

Abstract

Carcinoid tumors are rare and aggressive malignancies. A multitude of vasoactive agents are central to the systemic effects of these tumors. The additional burden of cardiac dysfunction heralds a steep decline in quality of life and survival. Unfortunately, by the time carcinoid syndrome surfaces clinically, the likelihood of cardiac involvement is 50%. Although medical therapies such as somatostatin analogues may provide some symptom relief, they offer no mortality benefit. On the other hand, referral to surgery following early detection has shown increased survival. The prompt recognition of this disease is therefore of the utmost importance.

Original languageEnglish (US)
Pages (from-to)789-795
Number of pages7
JournalAmerican Heart Journal
Volume167
Issue number6
DOIs
StatePublished - Jun 2014

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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