Cardiac allograft rejection monitored with ultrasound integrated backscatter

B. Hete, K. K. Shung, D. B. Campbell

Research output: Contribution to conferencePaperpeer-review

Abstract

Cardiac transplant rejection was evaluated using ultrasound integrated backscatter (IB). Six adult goats received modified Mann cervical heterotopic cardiac transplants with no administration of immunosuppressive pharmacology. A-line ultrasonic backscatter from the left ventricle was collected daily for each animal until the graft ceased to yield electrical activity. Integrated backscatter with a 4-8-MHz bandwidth was calculated for each day. No biopsies were taken. Although no consistent day-to-day trend is noted, four of six goats show a decrease in backscatter over the rejection episode. In all cases, the IB increased the first two to three days after the transplant and subsequently decreased in varying magnitudes and at varying durations.

Original languageEnglish (US)
Pages41-42
Number of pages2
StatePublished - Jan 1 1990
EventProceedings of the Sixteenth Annual Northeast Bioengineering Conference - University Park, PA, USA
Duration: Mar 26 1990Mar 27 1990

Other

OtherProceedings of the Sixteenth Annual Northeast Bioengineering Conference
CityUniversity Park, PA, USA
Period3/26/903/27/90

All Science Journal Classification (ASJC) codes

  • Bioengineering

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