Terapia de resincronización cardiaca: Evaluación de la disincronía ventricular y selección de pacientes

Translated title of the contribution: Cardiac resynchronization therapy: Evaluation of ventricular dysynchrony and patient selection

Giselle Baquero, Javier E. Banchs, William R. Davidson, Erica D. Penny-Peterson, Soraya M. Samii, Deborah L. Wolbrette, Gerald V. Naccarelli, Mario D. Gonzalez

Research output: Contribution to journalReview article

Abstract

Cardiac resynchronization therapy (CRT) is an established treatment modality for systolic heart failure. Aimed to produce simultaneous biventricular stimulation and correct the lack of ventricular synchrony in selected patients with congestive heart failure, CRT has shown to improve mortality and reduce hospital admissions when compared to medical treatment. At present, the indication criteria for the implantation of a CRT device include an ejection fraction of less than 35%, heart failure symptoms consistent with NYHA functional class III-IV and a QRS complex duration equal or longer than 120 milliseconds. It has been reported that 30% of patients who meet those criteria still may not derive clinical benefit from CRT. Due to the existing diversity of imaging modalities and resources for their process and analysis, a great expectation in terms of more accurate diagnosis of ventricular dyssynchrony has been raised. Reliable identification of dyssynchrony could allow us to better predict the favorable response of an individual patient to CRT and therefore offer this procedure to those individuals most likely to benefit. We review the available techniques for the study of ventricular dyssynchrony for CRT patient selection and the results of its application in clinical trials. Despite tremendous progress in the imaging technology available for the assessment and diagnosis of ventricular dyssynchrony, an ideal method has not been identified and the duration of the QRS complex in the surface ECG remains the accepted criteria of dyssynchrony in the selection of patients for CRT.

Original languageSpanish
Pages (from-to)289-300
Number of pages12
JournalArchivos de Cardiologia de Mexico
Volume80
Issue number4
StatePublished - Jan 1 2010

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Cardiac Resynchronization Therapy
Patient Selection
Cardiac Resynchronization Therapy Devices
Heart Failure
Systolic Heart Failure
Biomedical Technology Assessment
Hospital Mortality
Electrocardiography
Clinical Trials
Therapeutics

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

@article{f75413bbe6184316ad8ba59837059356,
title = "Terapia de resincronizaci{\'o}n cardiaca: Evaluaci{\'o}n de la disincron{\'i}a ventricular y selecci{\'o}n de pacientes",
abstract = "Cardiac resynchronization therapy (CRT) is an established treatment modality for systolic heart failure. Aimed to produce simultaneous biventricular stimulation and correct the lack of ventricular synchrony in selected patients with congestive heart failure, CRT has shown to improve mortality and reduce hospital admissions when compared to medical treatment. At present, the indication criteria for the implantation of a CRT device include an ejection fraction of less than 35{\%}, heart failure symptoms consistent with NYHA functional class III-IV and a QRS complex duration equal or longer than 120 milliseconds. It has been reported that 30{\%} of patients who meet those criteria still may not derive clinical benefit from CRT. Due to the existing diversity of imaging modalities and resources for their process and analysis, a great expectation in terms of more accurate diagnosis of ventricular dyssynchrony has been raised. Reliable identification of dyssynchrony could allow us to better predict the favorable response of an individual patient to CRT and therefore offer this procedure to those individuals most likely to benefit. We review the available techniques for the study of ventricular dyssynchrony for CRT patient selection and the results of its application in clinical trials. Despite tremendous progress in the imaging technology available for the assessment and diagnosis of ventricular dyssynchrony, an ideal method has not been identified and the duration of the QRS complex in the surface ECG remains the accepted criteria of dyssynchrony in the selection of patients for CRT.",
author = "Giselle Baquero and Banchs, {Javier E.} and Davidson, {William R.} and Penny-Peterson, {Erica D.} and Samii, {Soraya M.} and Wolbrette, {Deborah L.} and Naccarelli, {Gerald V.} and Gonzalez, {Mario D.}",
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day = "1",
language = "Spanish",
volume = "80",
pages = "289--300",
journal = "Archivos de Cardiologia de Mexico",
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Terapia de resincronización cardiaca : Evaluación de la disincronía ventricular y selección de pacientes. / Baquero, Giselle; Banchs, Javier E.; Davidson, William R.; Penny-Peterson, Erica D.; Samii, Soraya M.; Wolbrette, Deborah L.; Naccarelli, Gerald V.; Gonzalez, Mario D.

In: Archivos de Cardiologia de Mexico, Vol. 80, No. 4, 01.01.2010, p. 289-300.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Terapia de resincronización cardiaca

T2 - Evaluación de la disincronía ventricular y selección de pacientes

AU - Baquero, Giselle

AU - Banchs, Javier E.

AU - Davidson, William R.

AU - Penny-Peterson, Erica D.

AU - Samii, Soraya M.

AU - Wolbrette, Deborah L.

AU - Naccarelli, Gerald V.

AU - Gonzalez, Mario D.

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Cardiac resynchronization therapy (CRT) is an established treatment modality for systolic heart failure. Aimed to produce simultaneous biventricular stimulation and correct the lack of ventricular synchrony in selected patients with congestive heart failure, CRT has shown to improve mortality and reduce hospital admissions when compared to medical treatment. At present, the indication criteria for the implantation of a CRT device include an ejection fraction of less than 35%, heart failure symptoms consistent with NYHA functional class III-IV and a QRS complex duration equal or longer than 120 milliseconds. It has been reported that 30% of patients who meet those criteria still may not derive clinical benefit from CRT. Due to the existing diversity of imaging modalities and resources for their process and analysis, a great expectation in terms of more accurate diagnosis of ventricular dyssynchrony has been raised. Reliable identification of dyssynchrony could allow us to better predict the favorable response of an individual patient to CRT and therefore offer this procedure to those individuals most likely to benefit. We review the available techniques for the study of ventricular dyssynchrony for CRT patient selection and the results of its application in clinical trials. Despite tremendous progress in the imaging technology available for the assessment and diagnosis of ventricular dyssynchrony, an ideal method has not been identified and the duration of the QRS complex in the surface ECG remains the accepted criteria of dyssynchrony in the selection of patients for CRT.

AB - Cardiac resynchronization therapy (CRT) is an established treatment modality for systolic heart failure. Aimed to produce simultaneous biventricular stimulation and correct the lack of ventricular synchrony in selected patients with congestive heart failure, CRT has shown to improve mortality and reduce hospital admissions when compared to medical treatment. At present, the indication criteria for the implantation of a CRT device include an ejection fraction of less than 35%, heart failure symptoms consistent with NYHA functional class III-IV and a QRS complex duration equal or longer than 120 milliseconds. It has been reported that 30% of patients who meet those criteria still may not derive clinical benefit from CRT. Due to the existing diversity of imaging modalities and resources for their process and analysis, a great expectation in terms of more accurate diagnosis of ventricular dyssynchrony has been raised. Reliable identification of dyssynchrony could allow us to better predict the favorable response of an individual patient to CRT and therefore offer this procedure to those individuals most likely to benefit. We review the available techniques for the study of ventricular dyssynchrony for CRT patient selection and the results of its application in clinical trials. Despite tremendous progress in the imaging technology available for the assessment and diagnosis of ventricular dyssynchrony, an ideal method has not been identified and the duration of the QRS complex in the surface ECG remains the accepted criteria of dyssynchrony in the selection of patients for CRT.

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JO - Archivos de Cardiologia de Mexico

JF - Archivos de Cardiologia de Mexico

SN - 1405-9940

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