Cardiorespiratory components of defense reaction elicited from paraventricular nucleus

Yu-Fei Duan, Ray Winters, Philip M. McCabe, Edward J. Green, Ying Huang, Neil Schneiderman

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

The present study was conducted to test the hypothesis that the paraventricular nucleus of the hypothalamus (PVN) is involved in the mediation or modulation of the cardiorespiratory components of the defense reaction (DR) in rabbits. Electrical stimulation of the PVN elicited increases in blood pressure and heart rate, hyperventilation, decreased blood flow to the visceral organs, and an increase in blood flow to the hindlimbs that was mediated by an atropine-sensitive vasodilation system. This response pattern is nearly identical to the one that is elicited by electrical stimulation of the hypothalamic defense area. In addition, the cardiomotor component of the baroreceptor reflex was observed to be suppressed during electrical stimulation of the PVN. Previous studies have shown that electrical stimulation of the hypothalamic defense area also leads to inhibition of the cardiomotor component of the baroreceptor reflex. The results of the present study provide evidence that the PVN is involved in the mediation or modulation of the defense reaction.

Original languageEnglish (US)
Pages (from-to)325-330
Number of pages6
JournalPhysiology and Behavior
Volume61
Issue number2
DOIs
StatePublished - Jan 1 1997

Fingerprint

Paraventricular Hypothalamic Nucleus
Electric Stimulation
Hypothalamus
Baroreflex
Hyperventilation
Hindlimb
Atropine
Vasodilation
Heart Rate
Rabbits
Blood Pressure

All Science Journal Classification (ASJC) codes

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

Cite this

Duan, Yu-Fei ; Winters, Ray ; McCabe, Philip M. ; Green, Edward J. ; Huang, Ying ; Schneiderman, Neil. / Cardiorespiratory components of defense reaction elicited from paraventricular nucleus. In: Physiology and Behavior. 1997 ; Vol. 61, No. 2. pp. 325-330.
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Cardiorespiratory components of defense reaction elicited from paraventricular nucleus. / Duan, Yu-Fei; Winters, Ray; McCabe, Philip M.; Green, Edward J.; Huang, Ying; Schneiderman, Neil.

In: Physiology and Behavior, Vol. 61, No. 2, 01.01.1997, p. 325-330.

Research output: Contribution to journalArticle

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