Caregiver satisfaction with a multisite trial of atomoxetine and parent training for attention-deficit/hyperactivity disorder and behavioral noncompliance in children with autism spectrum disorder

Jill A. Hollway, Michael G. Aman, Marissa Imee Mendoza-Burcham, Laura Silverman, L. Eugene Arnold, Rameshwari Tumuluru, Benjamin L. Handen, Luc Lecavalier, Kristin Page, Pamela Sayre, Tristram Smith

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: The purpose of this study was to examine caregiver satisfaction with the research experience in a randomized clinical trial of atomoxetine (ATX) and parent training (PT) for attention-deficit/hyperactivity disorder (ADHD) and behavioral noncompliance co-occurring with autism. Methods: The Children with Hyperactivity and Autism Research Treatment Study (CHARTS) randomly assigned 128 children 5.00-14.11 years of age to four treatment groups (ATX + PT, ATX alone, PT + placebo[PBO], and PBO). Caregivers completed an 18 item questionnaire about their satisfaction with the research experience. We summarized caregiver responses with descriptive statistics and examined whether the responses were associated with demographic variables, treatment assignment, or the child's response to treatment (positive or negative). Results: Ninety-three percent of caregivers (119) completed the questionnaire. When asked if they would join the study again if given the chance, 87% (103) responded "yes," 13% (15) responded "maybe," and 1% (1) responded "no." When asked if they would recommend the study to other caregivers of children with similar problems, 92% (109) responded "yes" and 8% responded (10) "maybe." Of the 59 Parent Satisfaction Questionnaire (PSQ) respondents who received PT, 75% (44) felt more confident in managing current child behaviors, 24% (14) felt that their level of confidence was unchanged, and 2% (1) felt less confident. Most caregivers expressed satisfaction with the study procedures, including the number of visits and the safety monitoring protocols. Conclusions: In general, caregivers were highly satisfied with their research experience. These findings may be useful for informing human subject committees and for designing study protocols that are appealing to families.

Original languageEnglish (US)
Pages (from-to)807-814
Number of pages8
JournalJournal of Child and Adolescent Psychopharmacology
Volume26
Issue number9
DOIs
StatePublished - Nov 1 2016

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Attention Deficit Disorder with Hyperactivity
Caregivers
Autistic Disorder
Research
Placebos
Child Behavior
Therapeutics
Atomoxetine Hydrochloride
Autism Spectrum Disorder
Randomized Controlled Trials
Demography
Safety
Surveys and Questionnaires

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Psychiatry and Mental health
  • Pharmacology (medical)

Cite this

Hollway, Jill A. ; Aman, Michael G. ; Mendoza-Burcham, Marissa Imee ; Silverman, Laura ; Arnold, L. Eugene ; Tumuluru, Rameshwari ; Handen, Benjamin L. ; Lecavalier, Luc ; Page, Kristin ; Sayre, Pamela ; Smith, Tristram. / Caregiver satisfaction with a multisite trial of atomoxetine and parent training for attention-deficit/hyperactivity disorder and behavioral noncompliance in children with autism spectrum disorder. In: Journal of Child and Adolescent Psychopharmacology. 2016 ; Vol. 26, No. 9. pp. 807-814.
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Caregiver satisfaction with a multisite trial of atomoxetine and parent training for attention-deficit/hyperactivity disorder and behavioral noncompliance in children with autism spectrum disorder. / Hollway, Jill A.; Aman, Michael G.; Mendoza-Burcham, Marissa Imee; Silverman, Laura; Arnold, L. Eugene; Tumuluru, Rameshwari; Handen, Benjamin L.; Lecavalier, Luc; Page, Kristin; Sayre, Pamela; Smith, Tristram.

In: Journal of Child and Adolescent Psychopharmacology, Vol. 26, No. 9, 01.11.2016, p. 807-814.

Research output: Contribution to journalArticle

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T1 - Caregiver satisfaction with a multisite trial of atomoxetine and parent training for attention-deficit/hyperactivity disorder and behavioral noncompliance in children with autism spectrum disorder

AU - Hollway, Jill A.

AU - Aman, Michael G.

AU - Mendoza-Burcham, Marissa Imee

AU - Silverman, Laura

AU - Arnold, L. Eugene

AU - Tumuluru, Rameshwari

AU - Handen, Benjamin L.

AU - Lecavalier, Luc

AU - Page, Kristin

AU - Sayre, Pamela

AU - Smith, Tristram

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Objective: The purpose of this study was to examine caregiver satisfaction with the research experience in a randomized clinical trial of atomoxetine (ATX) and parent training (PT) for attention-deficit/hyperactivity disorder (ADHD) and behavioral noncompliance co-occurring with autism. Methods: The Children with Hyperactivity and Autism Research Treatment Study (CHARTS) randomly assigned 128 children 5.00-14.11 years of age to four treatment groups (ATX + PT, ATX alone, PT + placebo[PBO], and PBO). Caregivers completed an 18 item questionnaire about their satisfaction with the research experience. We summarized caregiver responses with descriptive statistics and examined whether the responses were associated with demographic variables, treatment assignment, or the child's response to treatment (positive or negative). Results: Ninety-three percent of caregivers (119) completed the questionnaire. When asked if they would join the study again if given the chance, 87% (103) responded "yes," 13% (15) responded "maybe," and 1% (1) responded "no." When asked if they would recommend the study to other caregivers of children with similar problems, 92% (109) responded "yes" and 8% responded (10) "maybe." Of the 59 Parent Satisfaction Questionnaire (PSQ) respondents who received PT, 75% (44) felt more confident in managing current child behaviors, 24% (14) felt that their level of confidence was unchanged, and 2% (1) felt less confident. Most caregivers expressed satisfaction with the study procedures, including the number of visits and the safety monitoring protocols. Conclusions: In general, caregivers were highly satisfied with their research experience. These findings may be useful for informing human subject committees and for designing study protocols that are appealing to families.

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DO - 10.1089/cap.2015.0130

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