Cartwright blood group system review

Research output: Contribution to journalReview article

Abstract

The Cartwright (Yt) blood group system consists of two antigens, Yta and Ytb, that result from point mutations in the acetylcholinesterase gene on chromosome 7q. Yta is a highincidence antigen, whereas its antithetical antigen, Ytb, shows much lower incidence. Anti-Yta and anti-Ytb are relatively rare. Anti-Yta is more commonly found in individuals of Jewish descent. Cartwright antibodies are rarely clinically significant; however, cases of in vivo hemolysis have been reported, suggesting that clinical significance should be interpreted on a case-by-case basis.

Original languageEnglish (US)
Pages (from-to)49-54
Number of pages6
JournalImmunohematology
Volume28
Issue number2
StatePublished - Dec 1 2012

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Hematology

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