Case of colonic mucosal Schwann cell hamartoma and review of literature on unusual colonic polyps

Jaya Krishna Chintanaboina, Kofi Clarke

Research output: Contribution to journalArticle

Abstract

Mucosal Schwann cell hamartomas (MSCH) are benign mesenchymal tumours rarely seen in the gastrointestinal tract. They occasionally present as incidental sessile polyps during colonoscopy. A 55-year-old asymptomatic female patient with a medical history of multiple sclerosis presented for a screening colonoscopy. A 5 mm low-risk tubular adenoma was noted in the caecum, and a second 5 mm polyp was found in the ascending colon. Histopathology of the ascending colon polyp showed proliferation of spindle cells without ganglion cells in the lamina propria. Immunohistochemical findings are compatible with an MSCH. Surveillance colonoscopy was scheduled in 5 years based on the presence of a single low-risk tubular adenoma.

Original languageEnglish (US)
Article numberbcr-2018-224931
JournalBMJ Case Reports
Volume2018
DOIs
StatePublished - Jan 1 2018

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Colonic Polyps
Hamartoma
Schwann Cells
Colonoscopy
Polyps
Ascending Colon
Adenoma
Ganglia
Multiple Sclerosis
Gastrointestinal Tract
Mucous Membrane
Cell Proliferation
Neoplasms

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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abstract = "Mucosal Schwann cell hamartomas (MSCH) are benign mesenchymal tumours rarely seen in the gastrointestinal tract. They occasionally present as incidental sessile polyps during colonoscopy. A 55-year-old asymptomatic female patient with a medical history of multiple sclerosis presented for a screening colonoscopy. A 5 mm low-risk tubular adenoma was noted in the caecum, and a second 5 mm polyp was found in the ascending colon. Histopathology of the ascending colon polyp showed proliferation of spindle cells without ganglion cells in the lamina propria. Immunohistochemical findings are compatible with an MSCH. Surveillance colonoscopy was scheduled in 5 years based on the presence of a single low-risk tubular adenoma.",
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Case of colonic mucosal Schwann cell hamartoma and review of literature on unusual colonic polyps. / Chintanaboina, Jaya Krishna; Clarke, Kofi.

In: BMJ Case Reports, Vol. 2018, bcr-2018-224931, 01.01.2018.

Research output: Contribution to journalArticle

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