Abstract
A 3-year-old patient with acute myelogenous leukemia developed fever and chills during transfusion of packed red cells. A preliminary workup suggested that a group AB donor unit had been issued to a Group A patient. However, a discrepancy between the ABO group of the original donor unit segment (A) and blood taken from the IV tubing (AB) and the patient's pre- and posttransfusion samples (A and AB, respectively) suggested another reason for the weak reactivity of some samples with anti-B. The patient's chart revealed that vancomycin, reported to be a cause of non-immune agglutination of red cells, had been injected into the IV tubing one hour prior to transfusion. Further testing confirmed that the patient's febrile response to transfusion was consistent with a nonhemolytic transfusion reaction and was unrelated to the drug-induced, pseudo ABO problem.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 119-124 |
| Number of pages | 6 |
| Journal | Immunohematology |
| Volume | 5 |
| Issue number | 4 |
| State | Published - Dec 1 1989 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
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Case report : ABO discrepancy due to vancomycin complicating a transfusion reaction investigation. / Gilbert, D. M.; Domen, Ronald.
In: Immunohematology, Vol. 5, No. 4, 01.12.1989, p. 119-124.Research output: Contribution to journal › Article
TY - JOUR
T1 - Case report
T2 - ABO discrepancy due to vancomycin complicating a transfusion reaction investigation
AU - Gilbert, D. M.
AU - Domen, Ronald
PY - 1989/12/1
Y1 - 1989/12/1
N2 - A 3-year-old patient with acute myelogenous leukemia developed fever and chills during transfusion of packed red cells. A preliminary workup suggested that a group AB donor unit had been issued to a Group A patient. However, a discrepancy between the ABO group of the original donor unit segment (A) and blood taken from the IV tubing (AB) and the patient's pre- and posttransfusion samples (A and AB, respectively) suggested another reason for the weak reactivity of some samples with anti-B. The patient's chart revealed that vancomycin, reported to be a cause of non-immune agglutination of red cells, had been injected into the IV tubing one hour prior to transfusion. Further testing confirmed that the patient's febrile response to transfusion was consistent with a nonhemolytic transfusion reaction and was unrelated to the drug-induced, pseudo ABO problem.
AB - A 3-year-old patient with acute myelogenous leukemia developed fever and chills during transfusion of packed red cells. A preliminary workup suggested that a group AB donor unit had been issued to a Group A patient. However, a discrepancy between the ABO group of the original donor unit segment (A) and blood taken from the IV tubing (AB) and the patient's pre- and posttransfusion samples (A and AB, respectively) suggested another reason for the weak reactivity of some samples with anti-B. The patient's chart revealed that vancomycin, reported to be a cause of non-immune agglutination of red cells, had been injected into the IV tubing one hour prior to transfusion. Further testing confirmed that the patient's febrile response to transfusion was consistent with a nonhemolytic transfusion reaction and was unrelated to the drug-induced, pseudo ABO problem.
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M3 - Article
VL - 5
SP - 119
EP - 124
JO - Immunohematology
JF - Immunohematology
SN - 0894-203X
IS - 4
ER -