Case study: An infection-triggered, autoimmune subtype of anorexia nervosa

Mae S. Sokol, Nicola S. Gray

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Objective: Certain cases of anorexia nervosa (AN) may be similar to the recently described subtype of childhood-onset obsessive-compulsive disorder hypothesized to be one of the pediatric infection-triggered autoimmune neuropsychiatric disorders (PITANDs). Method: Three clinical cases are reported. The first patient is a 12-year-old boy whose AN worsened acutely after a group A β-hemolytic streptococcal (GABHS) infection. His symptoms were alleviated after antibiotic treatment. Two other patients with possible PITANDs-related AN are described. Results: An infection-triggered process may contribute to the pathogenesis of a subtype of AN. Conclusions: Future research is needed to explore the nature of PITANDs and their relationship with AN.

Original languageEnglish (US)
Pages (from-to)1128-1133
Number of pages6
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Issue number8
StatePublished - Aug 1997

All Science Journal Classification (ASJC) codes

  • Developmental and Educational Psychology
  • Psychiatry and Mental health


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