Abstract
Perineuritis unassociated with other significant pathological changes is a rare finding. A patient is described with mild, non‐insulin dependent diabetes mellitus who presented with the clinical picture of mononeuritis multiplex, and in whom perineuritis but no occlusive vascular disease was found on sural nerve biopsy. Treatment with prednisone and plasma exchange resulted in some improvement. We conclude that the focal perineuritis, rather than the diabetes, was responsible for the clinical picture mimicking mononeuritis multiplex. In conjunction with previous reports, this suggests that perineuritis may be a treatable neuropathy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 630-635 |
| Number of pages | 6 |
| Journal | Muscle & nerve |
| Volume | 15 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 1992 |
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All Science Journal Classification (ASJC) codes
- Physiology
- Clinical Neurology
- Cellular and Molecular Neuroscience
- Physiology (medical)
Cite this
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Case‐of‐the‐month : Perineuritis presenting as mononeuritis multiplex. / Simmons, Zachary; Albers, James W.; Sima, Anders A.F.
In: Muscle & nerve, Vol. 15, No. 5, 05.1992, p. 630-635.Research output: Contribution to journal › Article
TY - JOUR
T1 - Case‐of‐the‐month
T2 - Perineuritis presenting as mononeuritis multiplex
AU - Simmons, Zachary
AU - Albers, James W.
AU - Sima, Anders A.F.
PY - 1992/5
Y1 - 1992/5
N2 - Perineuritis unassociated with other significant pathological changes is a rare finding. A patient is described with mild, non‐insulin dependent diabetes mellitus who presented with the clinical picture of mononeuritis multiplex, and in whom perineuritis but no occlusive vascular disease was found on sural nerve biopsy. Treatment with prednisone and plasma exchange resulted in some improvement. We conclude that the focal perineuritis, rather than the diabetes, was responsible for the clinical picture mimicking mononeuritis multiplex. In conjunction with previous reports, this suggests that perineuritis may be a treatable neuropathy.
AB - Perineuritis unassociated with other significant pathological changes is a rare finding. A patient is described with mild, non‐insulin dependent diabetes mellitus who presented with the clinical picture of mononeuritis multiplex, and in whom perineuritis but no occlusive vascular disease was found on sural nerve biopsy. Treatment with prednisone and plasma exchange resulted in some improvement. We conclude that the focal perineuritis, rather than the diabetes, was responsible for the clinical picture mimicking mononeuritis multiplex. In conjunction with previous reports, this suggests that perineuritis may be a treatable neuropathy.
UR - http://www.scopus.com/inward/record.url?scp=0026548716&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026548716&partnerID=8YFLogxK
U2 - 10.1002/mus.880150516
DO - 10.1002/mus.880150516
M3 - Article
C2 - 1584256
AN - SCOPUS:0026548716
VL - 15
SP - 630
EP - 635
JO - Muscle and Nerve
JF - Muscle and Nerve
SN - 0148-639X
IS - 5
ER -