CD4 +CD25 +Foxp3 regulatoryTcells and vascular dysfunction in hypertension

Modar Kassan, Andrea Wecker, Philip Kadowitz, Mohamed Trebak, Khalid Matrougui

Research output: Contribution to journalReview article

29 Citations (Scopus)

Abstract

Endothelial dysfunction plays a key role in the development and progression of cardiovascular disease. In patients with hypertension, endothelial dysfunction is characterized by a decrease of vasodilator factors release. Recent evidence highlights the involvement of regulatory T cell in the cardiovascular physiology and pathology. An increasing body of data suggest that an imbalance in the immune system triggers inflammation and compromises the cardiovascular homeostasis. In this mini-review, we will highlight the role of immune regulatory T cells in hypertension-induced vascular dysfunction.

Original languageEnglish (US)
Pages (from-to)1939-1943
Number of pages5
JournalJournal of hypertension
Volume31
Issue number10
DOIs
StatePublished - Oct 1 2013

Fingerprint

Regulatory T-Lymphocytes
Blood Vessels
Cardiovascular Physiological Phenomena
Hypertension
Vasodilator Agents
Immune System
Homeostasis
Cardiovascular Diseases
Pathology
Inflammation

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Kassan, Modar ; Wecker, Andrea ; Kadowitz, Philip ; Trebak, Mohamed ; Matrougui, Khalid. / CD4 +CD25 +Foxp3 regulatoryTcells and vascular dysfunction in hypertension. In: Journal of hypertension. 2013 ; Vol. 31, No. 10. pp. 1939-1943.
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CD4 +CD25 +Foxp3 regulatoryTcells and vascular dysfunction in hypertension. / Kassan, Modar; Wecker, Andrea; Kadowitz, Philip; Trebak, Mohamed; Matrougui, Khalid.

In: Journal of hypertension, Vol. 31, No. 10, 01.10.2013, p. 1939-1943.

Research output: Contribution to journalReview article

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