Cell competition and its possible relation to cancer

Nicholas E. Baker, Wei Li

Research output: Contribution to journalReview article

57 Citations (Scopus)

Abstract

Cell competition can occur when cells of different genotypes share the same developing compartment, with one genotype displacing the other as a result of a proliferative advantage. Studies of cell competition in Drosophila have identified an active process of cell assassination and corpse engulfment, and also roles for Myc and the Warts/Hippo tumor suppressor pathway. Here, we discuss the possible relevance of cell competition to cancer.

Original languageEnglish (US)
Pages (from-to)5505-5507
Number of pages3
JournalCancer Research
Volume68
Issue number14
DOIs
StatePublished - Jul 15 2008

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Neoplasms
Genotype
Warts
Cadaver
Drosophila

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Baker, Nicholas E. ; Li, Wei. / Cell competition and its possible relation to cancer. In: Cancer Research. 2008 ; Vol. 68, No. 14. pp. 5505-5507.
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Cell competition and its possible relation to cancer. / Baker, Nicholas E.; Li, Wei.

In: Cancer Research, Vol. 68, No. 14, 15.07.2008, p. 5505-5507.

Research output: Contribution to journalReview article

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