Central serous chorioretinopathy in women

D. A. Quillen, J. D.M. Gass, R. D. Brod, T. W. Gardner, G. W. Blankenship, J. L. Gottlieb

Research output: Contribution to journalArticlepeer-review

78 Scopus citations

Abstract

Background: Central serous chorioretinopathy is a disorder that typically affects young and middle-aged men. Although extensive information is available pertaining to the clinical features of central serous chorioretinopathy in men, little is known about this condition in women. Materials and Methods: The authors reviewed the medical records and photographic files of women who received a diagnosis of central serous chorioretinopathy. The women were divided into three groups for data analysis: idiopathic, exogenous corticosteroid use, and pregnancy. Results: Fifty-one women with active central serous chorioretinopathy were evaluated. The findings in women with idiopathic central serous chorioretinopathy were similar to those described in men, with the exception that women tend to be older at the time of onset. Central serous chorioretinopathy in women taking exogenous corticosteroids more likely was characterized by bilateral involvement and subretinal fibrin. Central serous chorioretinopathy in pregnant women typically developed in the third trimester and resolved spontaneously within 1-2 months after delivery. Conclusion: Idiopathic central serous chorioretinopathy is similar in women and men, with the exception that women tend to be older at the time of onset. The finding of exogenous corticosteroid use in a significant number of women in our study provides further support that cortisol may play a role in the development of central serous chorioretinopathy. The mechanism by which cortisol influences the development of central serous chorioretinopathy is unclear.

Original languageEnglish (US)
Pages (from-to)72-79
Number of pages8
JournalOphthalmology
Volume103
Issue number1
DOIs
StatePublished - 1996

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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