Challenges and progress toward quantitative deformation morphometry of gyral anatomy

C. Studholme, Corina Stefania Drapaca, V. Cardenas, M. Weiner

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper examines recent work toward quantitative mapping of cross-sectional structural differences in gyral anatomy. Taking the approach of deformation based morphometry, it examines an alternative method of calibrating the spatial filtering used in the statistical analysis of maps of relative tissue volume. This differs fundamentally from many common studies based on voxel morphometry. Rather than applying spatial filtering to simply create a significant statistical effect, filtering can be applied in a way which optimizes the qualitative accuracy of the maps with respect to structures of interest, allowing inferences to be made about the effect of a degenerative disease on the amount of tissue on a given region of anatomy. Results using this approach are included from a recent cross sectional study of Semantic Dementia.

Original languageEnglish (US)
Title of host publication2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationMacro to Nano
Pages599-602
Number of pages4
StatePublished - Dec 1 2004
Event2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States
Duration: Apr 15 2004Apr 18 2004

Publication series

Name2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Volume1

Other

Other2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
CountryUnited States
CityArlington, VA
Period4/15/044/18/04

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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  • Cite this

    Studholme, C., Drapaca, C. S., Cardenas, V., & Weiner, M. (2004). Challenges and progress toward quantitative deformation morphometry of gyral anatomy. In 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (pp. 599-602). (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 1).