Changes in the control of skin blood flow with exercise training

Where do cutaneous vascular adaptations fit in?

Grant H. Simmons, Brett J. Wong, Lacy Marie Alexander, William Lawrence Kenney, Jr.

Research output: Contribution to journalReview article

43 Citations (Scopus)

Abstract

Heat is the most abundant byproduct of cellular metabolism. As such, dynamic exercise in which a significant percentage of muscle mass is engaged generates thermoregulatory demands that are met in part by increases in skin blood flow. Increased skin blood flow during exercise adds to the demands on cardiac output and confers additional circulatory strain beyond that associated with perfusion of active muscle alone. Endurance exercise training results in a number of physiological adaptations which ultimately reduce circulatory strain and shift thermoregulatory control of skin blood flow to higher levels of blood flow for a given core temperature. In addition, exercise training induces peripheral vascular adaptations within the cutaneous microvasculature indicative of enhanced endothelium-dependent vasomotor function. However, it is not currently clear how (or if) these local vascular adaptations contribute to the beneficial changes in thermoregulatory control of skin blood flow following exercise training. The purpose of this Hot Topic Review is to synthesize the literature pertaining to exercise training-mediated changes in cutaneous microvascular reactivity and thermoregulatory control of skin blood flow. In addition, we address mechanisms driving changes in cutaneous microvascular reactivity and thermoregulatory control of skin blood flow, and pose the question: what (if any) is the functional role of increased cutaneous microvascular reactivity following exercise training?.

Original languageEnglish (US)
Pages (from-to)822-828
Number of pages7
JournalExperimental Physiology
Volume96
Issue number9
DOIs
StatePublished - Jan 1 2011

Fingerprint

Blood Vessels
Exercise
Skin
Physiological Adaptation
Muscles
Microvessels
Cardiac Output
Endothelium
Perfusion
Hot Temperature
Temperature

All Science Journal Classification (ASJC) codes

  • Physiology

Cite this

@article{aa919ca2b24543bea815c88c093f2c1b,
title = "Changes in the control of skin blood flow with exercise training: Where do cutaneous vascular adaptations fit in?",
abstract = "Heat is the most abundant byproduct of cellular metabolism. As such, dynamic exercise in which a significant percentage of muscle mass is engaged generates thermoregulatory demands that are met in part by increases in skin blood flow. Increased skin blood flow during exercise adds to the demands on cardiac output and confers additional circulatory strain beyond that associated with perfusion of active muscle alone. Endurance exercise training results in a number of physiological adaptations which ultimately reduce circulatory strain and shift thermoregulatory control of skin blood flow to higher levels of blood flow for a given core temperature. In addition, exercise training induces peripheral vascular adaptations within the cutaneous microvasculature indicative of enhanced endothelium-dependent vasomotor function. However, it is not currently clear how (or if) these local vascular adaptations contribute to the beneficial changes in thermoregulatory control of skin blood flow following exercise training. The purpose of this Hot Topic Review is to synthesize the literature pertaining to exercise training-mediated changes in cutaneous microvascular reactivity and thermoregulatory control of skin blood flow. In addition, we address mechanisms driving changes in cutaneous microvascular reactivity and thermoregulatory control of skin blood flow, and pose the question: what (if any) is the functional role of increased cutaneous microvascular reactivity following exercise training?.",
author = "Simmons, {Grant H.} and Wong, {Brett J.} and Alexander, {Lacy Marie} and {Kenney, Jr.}, {William Lawrence}",
year = "2011",
month = "1",
day = "1",
doi = "10.1113/expphysiol.2010.056176",
language = "English (US)",
volume = "96",
pages = "822--828",
journal = "Experimental Physiology",
issn = "0958-0670",
publisher = "Wiley-Blackwell",
number = "9",

}

Changes in the control of skin blood flow with exercise training : Where do cutaneous vascular adaptations fit in? / Simmons, Grant H.; Wong, Brett J.; Alexander, Lacy Marie; Kenney, Jr., William Lawrence.

In: Experimental Physiology, Vol. 96, No. 9, 01.01.2011, p. 822-828.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Changes in the control of skin blood flow with exercise training

T2 - Where do cutaneous vascular adaptations fit in?

AU - Simmons, Grant H.

AU - Wong, Brett J.

AU - Alexander, Lacy Marie

AU - Kenney, Jr., William Lawrence

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Heat is the most abundant byproduct of cellular metabolism. As such, dynamic exercise in which a significant percentage of muscle mass is engaged generates thermoregulatory demands that are met in part by increases in skin blood flow. Increased skin blood flow during exercise adds to the demands on cardiac output and confers additional circulatory strain beyond that associated with perfusion of active muscle alone. Endurance exercise training results in a number of physiological adaptations which ultimately reduce circulatory strain and shift thermoregulatory control of skin blood flow to higher levels of blood flow for a given core temperature. In addition, exercise training induces peripheral vascular adaptations within the cutaneous microvasculature indicative of enhanced endothelium-dependent vasomotor function. However, it is not currently clear how (or if) these local vascular adaptations contribute to the beneficial changes in thermoregulatory control of skin blood flow following exercise training. The purpose of this Hot Topic Review is to synthesize the literature pertaining to exercise training-mediated changes in cutaneous microvascular reactivity and thermoregulatory control of skin blood flow. In addition, we address mechanisms driving changes in cutaneous microvascular reactivity and thermoregulatory control of skin blood flow, and pose the question: what (if any) is the functional role of increased cutaneous microvascular reactivity following exercise training?.

AB - Heat is the most abundant byproduct of cellular metabolism. As such, dynamic exercise in which a significant percentage of muscle mass is engaged generates thermoregulatory demands that are met in part by increases in skin blood flow. Increased skin blood flow during exercise adds to the demands on cardiac output and confers additional circulatory strain beyond that associated with perfusion of active muscle alone. Endurance exercise training results in a number of physiological adaptations which ultimately reduce circulatory strain and shift thermoregulatory control of skin blood flow to higher levels of blood flow for a given core temperature. In addition, exercise training induces peripheral vascular adaptations within the cutaneous microvasculature indicative of enhanced endothelium-dependent vasomotor function. However, it is not currently clear how (or if) these local vascular adaptations contribute to the beneficial changes in thermoregulatory control of skin blood flow following exercise training. The purpose of this Hot Topic Review is to synthesize the literature pertaining to exercise training-mediated changes in cutaneous microvascular reactivity and thermoregulatory control of skin blood flow. In addition, we address mechanisms driving changes in cutaneous microvascular reactivity and thermoregulatory control of skin blood flow, and pose the question: what (if any) is the functional role of increased cutaneous microvascular reactivity following exercise training?.

UR - http://www.scopus.com/inward/record.url?scp=80051930221&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80051930221&partnerID=8YFLogxK

U2 - 10.1113/expphysiol.2010.056176

DO - 10.1113/expphysiol.2010.056176

M3 - Review article

VL - 96

SP - 822

EP - 828

JO - Experimental Physiology

JF - Experimental Physiology

SN - 0958-0670

IS - 9

ER -