Changes in the microscopic anatomy of the bovine teat canal during mammary involution.

M. P. Comalli, R. J. Eberhart, Lester C. Griel, Jr., H. Rothenbacher

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Abstract

Changes in the microscopic anatomy of the bovine teat canal were examined during mammary involution. Morphometric analyses revealed a significant (P less than 0.05), temporary dilatation of the teat canal lumen on day 7 of the nonlactating period. Additionally, the teat canal epithelium physiologically atrophied as evidenced by decreased cross-sectional area and thickness during the first 30 days of the nonlactating period, significantly so (P less than 0.05) between days 0 and 7. This physiologic atrophy was due mainly to a reduction in area and thickness of the stratum granulosum and may have resulted from continuing keratinization, a process that led to increased thickness of the keratin layer and formation of a functional plug during later stages of involution. Changes in cells of the stratum granulosum indicated a decrease in the rate of epithelial cell maturation during involution. The mitotic index (percentage of basal cells in mitosis) of the teat canal epithelium decreased significantly (P less than 0.05) between days 0 and 7 of the nonlactating period. Bacteria, observed in histologic sections, appeared to colonize only certain regions of the keratin layer. Seemingly, changes in the teat canal during mammary involution may be important factors in changing susceptibility to new intramammary infection during the early and mid-nonlactating periods.

Original languageEnglish (US)
Pages (from-to)2236-2242
Number of pages7
JournalAmerican journal of veterinary research
Volume45
Issue number11
StatePublished - Nov 1 1984

All Science Journal Classification (ASJC) codes

  • veterinary(all)

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    Comalli, M. P., Eberhart, R. J., Griel, Jr., L. C., & Rothenbacher, H. (1984). Changes in the microscopic anatomy of the bovine teat canal during mammary involution. American journal of veterinary research, 45(11), 2236-2242.