Characteristics of acute transverse myelitis at Aga Khan University Hospital, Karachi

Arslan Akbar Kahloon, Hiba Arif, Shahid Masud Baig, Muhammad Khawaja

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective: To determine the presenting features and etiological classification of acute transverse myelitis (ATM) at Aga Khan University Hospital, a tertiary care hospital in Pakistan. Methods: Twenty consecutive patients of ATM (1990-2003) fulfilling a preset criterion were analyzed for demographic features, clinical presentation, laboratory investigations and neuro-imaging. Results: Half of the patients were males and their median age was 29 years (range 6-73 years). Fever, paraparesis, quadri-paresis and bladder dysfunction were the most common presentations. Median score on disability rating scale (DRS) was twelve. Sixty percent of the patients were classified as Idiopathic-ATM while 30% and 10% as Para infectious associated-ATM and Multiple sclerosis associated-ATM respectively. Conclusion: Idiopathic acute transverse myelitis is the most common type of ATM in the studied population. Our data suggested that the severity of motor impairment is greater in our population than that reported in western literature which might hint to different genetic or environmental etiological factors involved in the pathogenesis of acute transverse myelitis.

Original languageEnglish (US)
Pages (from-to)215-218
Number of pages4
JournalJournal of the Pakistan Medical Association
Volume57
Issue number4
StatePublished - Apr 1 2007

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Transverse Myelitis
Paraparesis
Pakistan
Paresis
Tertiary Healthcare
Tertiary Care Centers
Population
Multiple Sclerosis
Urinary Bladder
Fever
Demography

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kahloon, Arslan Akbar ; Arif, Hiba ; Baig, Shahid Masud ; Khawaja, Muhammad. / Characteristics of acute transverse myelitis at Aga Khan University Hospital, Karachi. In: Journal of the Pakistan Medical Association. 2007 ; Vol. 57, No. 4. pp. 215-218.
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Characteristics of acute transverse myelitis at Aga Khan University Hospital, Karachi. / Kahloon, Arslan Akbar; Arif, Hiba; Baig, Shahid Masud; Khawaja, Muhammad.

In: Journal of the Pakistan Medical Association, Vol. 57, No. 4, 01.04.2007, p. 215-218.

Research output: Contribution to journalArticle

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AB - Objective: To determine the presenting features and etiological classification of acute transverse myelitis (ATM) at Aga Khan University Hospital, a tertiary care hospital in Pakistan. Methods: Twenty consecutive patients of ATM (1990-2003) fulfilling a preset criterion were analyzed for demographic features, clinical presentation, laboratory investigations and neuro-imaging. Results: Half of the patients were males and their median age was 29 years (range 6-73 years). Fever, paraparesis, quadri-paresis and bladder dysfunction were the most common presentations. Median score on disability rating scale (DRS) was twelve. Sixty percent of the patients were classified as Idiopathic-ATM while 30% and 10% as Para infectious associated-ATM and Multiple sclerosis associated-ATM respectively. Conclusion: Idiopathic acute transverse myelitis is the most common type of ATM in the studied population. Our data suggested that the severity of motor impairment is greater in our population than that reported in western literature which might hint to different genetic or environmental etiological factors involved in the pathogenesis of acute transverse myelitis.

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