Characterization of LEF1 high expression and novel mutations in adult acute lymphoblastic leukemia

Medicine & Life Sciences

• Lymphoid Enhancer-Binding Factor 1 100%
• Precursor Cell Lymphoblastic Leukemia-Lymphoma 56%
• Mutation 32%
• Cyclin D1 14%
• Karyotype 9%
• Leukemia 7%
• Philadelphia Chromosome 5%
• Wnt Signaling Pathway 5%
• Progression-Free Survival 4%
• Cell Proliferation 2%
• Recurrence 2%
• Messenger RNA 2%
• Neoplasms 1%

Agriculture & Biology

• lymphocytic leukemia 79%
• mutation 39%
• cyclins 23%
• leukemia 13%
• leukocytes 11%
• gain-of-function mutation 10%
• relapse 8%
• mutation rate 6%
• cell proliferation 5%
• neoplasms 4%
• transcription (genetics) 4%
• promoter regions 4%
• chromosomes 4%
• mutants 3%
• cells 2%

Chemical Compounds

• Enhancer 68%
• Mutation 48%
• Chemical Transformation 2%