Characterization of thin biological tissue with scanning acoustic microscopy

Chiaki Miyasaka, Jikai Du, Bernhard R. Tittmann

Research output: Contribution to journalConference article

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Abstract

The present article reports a technique to measure velocity of a biological specimen, wherein the thickness of the biological specimen and the diameter of the measurement area of the specimen are in the order of a few microns. The kidney was selected for the specimen as an example of the soft material. The kidney was thinly sliced by a microtome and located on a substrate. The thickness of the specimen was substantially 3 μm. For the substrate, fused quartz was used because its elastic properties are known and stable. The spherical acoustic lens was used to determine the position for the measurement. The frequencies of 400 and 600 MHz were used for the measurement and the visualization respectively. The generation of the Rayleigh waves in the above conditions was simulated by numerical calculations based on the wave propagation theory for layered media.

Original languageEnglish (US)
Pages (from-to)27-32
Number of pages6
JournalAmerican Society of Mechanical Engineers, Pressure Vessels and Piping Division (Publication) PVP
Volume450
DOIs
Publication statusPublished - Dec 31 2002
EventThe 2002 ASME Pressure Vessels and Piping Conference: NDE Engineering Applications - Vancouver, BC, Canada
Duration: Aug 5 2002Aug 9 2002

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All Science Journal Classification (ASJC) codes

  • Mechanical Engineering

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