Biochemical reactions would open doors to the control of innumerable sophisticated, environmentally friendly, enzymatic, or other biological activities useful for self-regulating medical implants, such as biomolecule detection, separation, and signal amplification. Biochemical processes in general are typically sensitive to pH, temperature, and salt concentrations, requiring a narrow range to operate successfully. The rapid responsiveness and precise synchronization of the light emission and the microfin movement in and out of the reagent layer during multiple cycles are well evidenced by the time-resolved bioluminescence intensity. The proper function of the enzyme is further supported by the sustained luminescence through 30-40 actuation cycles. The SMARTS device is shown to be both compatible with delicate biological constraints and capable of accommodating enzymatic reactions for signal transduction, attributed to its modularity, tunability, and physical simplicity.
All Science Journal Classification (ASJC) codes
- Chemical Engineering(all)
- Materials Chemistry