Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection

Katharine E. Yoder, Michele L. Shaffer, Susan J. La Tournous, Ian Paul

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

This study sought to investigate the efficacy of dextromethorphan (DM), diphenhydramine (DPH), and placebo (PL) for symptoms attributed to upper respiratory infections as determined by children, and to evaluate the concordance of perception of nocturnal symptoms between children and parents. A total of 37 children age 6 to 18 years of age were randomized in a double-masked fashion to receive a single bedtime dose of DM, DPH, or PL. Children found no significant difference in the effect of DM, DPH, or PL for any study outcome, and responses by parents and children were significantly correlated.

Original languageEnglish (US)
Pages (from-to)633-640
Number of pages8
JournalClinical Pediatrics
Volume45
Issue number7
DOIs
StatePublished - Sep 1 2006

Fingerprint

Dextromethorphan
Diphenhydramine
Cough
Respiratory Tract Infections
Placebos
Parents
Outcome Assessment (Health Care)

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

Yoder, Katharine E. ; Shaffer, Michele L. ; La Tournous, Susan J. ; Paul, Ian. / Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection. In: Clinical Pediatrics. 2006 ; Vol. 45, No. 7. pp. 633-640.
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Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection. / Yoder, Katharine E.; Shaffer, Michele L.; La Tournous, Susan J.; Paul, Ian.

In: Clinical Pediatrics, Vol. 45, No. 7, 01.09.2006, p. 633-640.

Research output: Contribution to journalArticle

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