Chorioamnionitis: Implications for the neonate

Jessica E. Ericson; Matthew M. Laughon

doi:10.1016/j.clp.2014.10.011

Chorioamnionitis: Implications for the neonate

Jessica E. Ericson, Matthew M. Laughon

Research output: Contribution to journal › Review article

26 Scopus citations

Abstract

Chorioamnionitis (CA) is characterized by inflammation of the fetal membranes. The incidence increases with decreasing gestational age at birth. When suspected on clinical criteria, pathologic assessment of the placenta should be performed. Although the mechanisms are not entirely clear, CA predisposes to premature birth, neonatal sepsis, and intraventricular hemorrhage. Its role in respiratory distress syndrome, bronchopulmonary dysplasia, and neurodevelopmental impairment is mixed. Prevention and treatment are ill-defined; antibiotics for preterm premature rupture of membranes reduce the incidence and increase the length of time to delivery. Antibiotics are recommended for infants exposed to CA while laboratory studies are being performed.

Original language	English (US)
Pages (from-to)	155-165
Number of pages	11
Journal	Clinics in Perinatology
Volume	42
Issue number	1
DOIs	https://doi.org/10.1016/j.clp.2014.10.011
State	Published - Mar 1 2015

All Science Journal Classification (ASJC) codes

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1016/j.clp.2014.10.011

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Ericson, J. E., & Laughon, M. M. (2015). Chorioamnionitis: Implications for the neonate. Clinics in Perinatology, 42(1), 155-165. https://doi.org/10.1016/j.clp.2014.10.011

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