Chromosome-mediated transfer of the murine Na,K-ATPase alpha subunit confers ouabain resistance.

D. Fallows, R. B. Kent, D. L. Nelson, J. R. Emanuel, R. Levenson, D. E. Housman

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

We transferred murine NIH 3T3 metaphase chromosomes into monkey CV-1 cells to investigate the different ouabain sensitivities of rodent and primate cells. In 16 ouabain-resistant transferents, the mouse Na,K-ATPase alpha 1 subunit gene was detected, suggesting that structural differences between the rodent and primate alpha 1 subunits determine the different ouabain sensitivities.

Original languageEnglish (US)
Pages (from-to)2985-2987
Number of pages3
JournalMolecular and cellular biology
Volume7
Issue number8
DOIs
StatePublished - Aug 1987

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cell Biology

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