Chronic inflammatory demyelinating polyradiculoneuropathy

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is usually idiopathic and presents with relatively symmetric, progressive or relapsing weakness, sensory loss, and hypo- or areflexia. The key to diagnosis is the presence of a sensorimotor polyneuropathy with multifocal demyelination on electrodiagnostic examination. Most patients respond well to immunotherapy. Intravenous immunoglobulin is usually considered the treatment of first choice, although a variety of other immunotherapies including plasma exchange and corticosteroids are also effective. CIDP occurs less commonly in children than in adults, but is treated similarly, and usually has an excellent prognosis. CIDP may be associated with a monoclonal gammopathy of undetermined significance. When associated with IgM, deficits are primarily sensory and response to treatment is unreliable and often poor. In contrast, when associated with IgG or IgA, deficits and treatment are similarly to those with idiopathic CIDP. An asymmetric pattern of deficits occurs and treatment is similar to idiopathic CIDP.

Original languageEnglish (US)
Title of host publicationHandbook of Peripheral Neuropathy
PublisherCRC Press
Pages127-159
Number of pages33
ISBN (Electronic)9780849354861
ISBN (Print)9780824754327
StatePublished - Jan 1 2005

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Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Immunotherapy
Monoclonal Gammopathy of Undetermined Significance
Abnormal Reflexes
Plasma Exchange
Polyneuropathies
Intravenous Immunoglobulins
Demyelinating Diseases
Therapeutics
Immunoglobulin A
Immunoglobulin M
Adrenal Cortex Hormones
Immunoglobulin G

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Health Professions(all)

Cite this

Simmons, Z. (2005). Chronic inflammatory demyelinating polyradiculoneuropathy. In Handbook of Peripheral Neuropathy (pp. 127-159). CRC Press.
Simmons, Zachary. / Chronic inflammatory demyelinating polyradiculoneuropathy. Handbook of Peripheral Neuropathy. CRC Press, 2005. pp. 127-159
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Simmons, Z 2005, Chronic inflammatory demyelinating polyradiculoneuropathy. in Handbook of Peripheral Neuropathy. CRC Press, pp. 127-159.

Chronic inflammatory demyelinating polyradiculoneuropathy. / Simmons, Zachary.

Handbook of Peripheral Neuropathy. CRC Press, 2005. p. 127-159.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Simmons Z. Chronic inflammatory demyelinating polyradiculoneuropathy. In Handbook of Peripheral Neuropathy. CRC Press. 2005. p. 127-159