Chronic Insomnia and the Stress System

Maria Basta, George P. Chrousos, Antonio Vela-Bueno, Alexandros N. Vgontzas

Research output: Contribution to journalReview article

133 Citations (Scopus)

Abstract

In insomnia, which is a very common sleep disorder, objective sleep measures, EEG activity, physiologic findings, HPA axis activity, and inflammation markers suggest that it is not a state of sleep loss, but a disorder of hyperarousal present both during the night and the daytime. Several psychological and physiological factors contribute to the onset and perpetuation of insomnia, such as anxious-ruminative personality traits, stressful events, age-related sleep homeostasis weakening mechanisms, menopause, and biologic-genetic diathesis of CNS hyperarousal. The therapeutic approach in insomnia should be multidimensional, reducing the overall emotional and physiologic hyperarousal and its underlying factors present throughout the 24-hour sleep/wake period.

Original languageEnglish (US)
Pages (from-to)279-291
Number of pages13
JournalSleep Medicine Clinics
Volume2
Issue number2
DOIs
StatePublished - Jun 1 2007

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Sleep Initiation and Maintenance Disorders
Sleep
Disease Susceptibility
Menopause
Biological Products
Personality
Electroencephalography
Homeostasis
Psychology
Inflammation
Therapeutics

All Science Journal Classification (ASJC) codes

  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Basta, Maria ; Chrousos, George P. ; Vela-Bueno, Antonio ; Vgontzas, Alexandros N. / Chronic Insomnia and the Stress System. In: Sleep Medicine Clinics. 2007 ; Vol. 2, No. 2. pp. 279-291.
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Basta, M, Chrousos, GP, Vela-Bueno, A & Vgontzas, AN 2007, 'Chronic Insomnia and the Stress System', Sleep Medicine Clinics, vol. 2, no. 2, pp. 279-291. https://doi.org/10.1016/j.jsmc.2007.04.002

Chronic Insomnia and the Stress System. / Basta, Maria; Chrousos, George P.; Vela-Bueno, Antonio; Vgontzas, Alexandros N.

In: Sleep Medicine Clinics, Vol. 2, No. 2, 01.06.2007, p. 279-291.

Research output: Contribution to journalReview article

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