TY - JOUR
T1 - Clinical Decision Support for Glycemic Management Reduces Hospital Length of Stay
AU - Pichardo-Lowden, Ariana R.
AU - Haidet, Paul
AU - Umpierrez, Guillermo E.
AU - Lehman, Erik B.
AU - Quigley, Francis T.
AU - Wang, Li
AU - Rafferty, Colleen M.
AU - Deflitch, Christopher J.
AU - Chinchilli, Vernon M.
N1 - Funding Information:
Funding. A.R.P.-L. received support from National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) career development grant K23DK107914-05 for this project and is supported by NIDDK grant R01DK130992-01. G.E.U. is partly supported by National Center for Advancing Translational Sciences Clinical and Translational Science Award 3UL1TR002378-05S2 and NIDDK grant 2P30DK111024-06. Duality of Interest. G.E.U. has received unrestricted research support from AstraZeneca and Dexcom. No other potential conflicts of interest relevant to this article were reported. Author Contributions. A.R.P.-L. led the conduct of the project, including the study design; development and implementation of the alert-based CDS tool; data collection, analysis, and interpretation; and writing of the manuscript. P.H. advised on the study design and integrity and contributed to the interpretation of results and manuscript preparation, review, and edits. G.E.U. contributed to the study design, interpretation of findings, and manuscript review. E.B.L. contributed to the data management, analysis, and interpretation and manuscript preparation. F.T.Q. and L.W. contributed to the interpretation of findings and manuscript review. C.M.R. advised on the implementation of the alert-based CDS tool, review of findings, and manuscript review. C.J.D. contributed to implementation of the alert-based CDS tool, review of findings, and manuscript review. V.M.C. contributed to the study design, data analysis, interpretation of findings, and manuscript review. A.R.P.-L. is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Prior Presentation. Parts of this study were presented in abstract form at the NIDDK Network of Minority Research Investigators virtual meeting, 28–30 April 2021, and at the 15th Advanced Technology and Treatment for Diabetes, Barcelona, Spain, 27–30 April 2022.
Publisher Copyright:
© 2022 by the American Diabetes Association.
PY - 2022/11
Y1 - 2022/11
N2 - OBJECTIVE Dysglycemia influences hospital outcomes and resource utilization. Clinical decision support (CDS) holds promise for optimizing care by overcoming management barriers. This study assessed the impact on hospital length of stay (LOS) of an alert-based CDS tool in the electronic medical record that detected dysglycemia or inappropriate insulin use, coined as gaps in care (GIC). RESEARCH DESIGN AND METHODS Using a 12-month interrupted time series among hospitalized persons aged ‡18 years, our CDS tool identified GIC and, when active, provided recommendations. We compared LOS during 6-month-long active and inactive periods using linear models for repeated measures, multiple comparison adjustment, and mediation analysis. RESULTS Among 4,788 admissions with GIC, average LOS was shorter during the tool’s active periods. LOS reductions occurred for all admissions with GIC (25.7 h, P = 0.057), diabetes and hyperglycemia (26.4 h, P = 0.054), stress hyperglycemia (231.0 h, P = 0.054), patients admitted to medical services (28.4 h, P = 0.039), and recurrent hypoglycemia (229.1 h, P = 0.074). Subgroup analysis showed sig-nificantly shorter LOS in recurrent hypoglycemia with three events (282.3 h, P = 0.006) and nonsignificant in two (25.2 h, P = 0.655) and four or more (214.8 h, P = 0.746). Among 22,395 admissions with GIC (4,788, 21%) and without GIC (17,607, 79%), LOS reduction during the active period was 1.8 h (P = 0.053). When recommendations were provided, the active tool indirectly and signifi-cantly contributed to shortening LOS through its influence on GIC events during admissions with at least one GIC (P = 0.027), diabetes and hyperglycemia (P = 0.028), and medical services (P = 0.019). CONCLUSIONS Use of the alert-based CDS tool to address inpatient management of dysglycemia contributed to reducing LOS, which may reduce costs and improve patient well-being.
AB - OBJECTIVE Dysglycemia influences hospital outcomes and resource utilization. Clinical decision support (CDS) holds promise for optimizing care by overcoming management barriers. This study assessed the impact on hospital length of stay (LOS) of an alert-based CDS tool in the electronic medical record that detected dysglycemia or inappropriate insulin use, coined as gaps in care (GIC). RESEARCH DESIGN AND METHODS Using a 12-month interrupted time series among hospitalized persons aged ‡18 years, our CDS tool identified GIC and, when active, provided recommendations. We compared LOS during 6-month-long active and inactive periods using linear models for repeated measures, multiple comparison adjustment, and mediation analysis. RESULTS Among 4,788 admissions with GIC, average LOS was shorter during the tool’s active periods. LOS reductions occurred for all admissions with GIC (25.7 h, P = 0.057), diabetes and hyperglycemia (26.4 h, P = 0.054), stress hyperglycemia (231.0 h, P = 0.054), patients admitted to medical services (28.4 h, P = 0.039), and recurrent hypoglycemia (229.1 h, P = 0.074). Subgroup analysis showed sig-nificantly shorter LOS in recurrent hypoglycemia with three events (282.3 h, P = 0.006) and nonsignificant in two (25.2 h, P = 0.655) and four or more (214.8 h, P = 0.746). Among 22,395 admissions with GIC (4,788, 21%) and without GIC (17,607, 79%), LOS reduction during the active period was 1.8 h (P = 0.053). When recommendations were provided, the active tool indirectly and signifi-cantly contributed to shortening LOS through its influence on GIC events during admissions with at least one GIC (P = 0.027), diabetes and hyperglycemia (P = 0.028), and medical services (P = 0.019). CONCLUSIONS Use of the alert-based CDS tool to address inpatient management of dysglycemia contributed to reducing LOS, which may reduce costs and improve patient well-being.
UR - http://www.scopus.com/inward/record.url?scp=85141362608&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85141362608&partnerID=8YFLogxK
U2 - 10.2337/dc21-0829
DO - 10.2337/dc21-0829
M3 - Article
C2 - 36084251
AN - SCOPUS:85141362608
SN - 1935-5548
VL - 45
SP - 2526
EP - 2534
JO - Diabetes Care
JF - Diabetes Care
IS - 11
ER -