Colon and rectal carcinoma

David Soybel, David P. Bliss, Samuel A. Wells

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

In the United States the incidence of carcinoma of the colon or rectum appears to be increasing. Although certain dietary habits appear to be associated with disease incidence, the putative carcinogens in the lumen of the bowel remain unidentified. The use of clinical screening based on a combination of proctosigmoidoscopy and tests for occult fecal blood allows detection of colorectal carcinomas at an early stage; however, it is unclear whether such screening is cost-effective in persons over 40 years of age or if treatment undertaken on the basis of screening results truly alters the natural history of the disease. Surgical resection is the mainstay of curative therapy, and its effectiveness will probably be enhanced by adjuvant x-ray therapy and chemotherapy.

Original languageEnglish (US)
Pages (from-to)259-356
Number of pages98
JournalCurrent Problems in Cancer
Volume9
Issue number5
DOIs
StatePublished - Jan 1 1987

Fingerprint

Colon
Carcinoma
Sigmoidoscopy
Occult Blood
Incidence
Feeding Behavior
Rectum
Carcinogens
Colorectal Neoplasms
Therapeutics
X-Rays
Costs and Cost Analysis
Drug Therapy

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Soybel, David ; Bliss, David P. ; Wells, Samuel A. / Colon and rectal carcinoma. In: Current Problems in Cancer. 1987 ; Vol. 9, No. 5. pp. 259-356.
@article{368c57093c174d94ba2deb2bc05e9506,
title = "Colon and rectal carcinoma",
abstract = "In the United States the incidence of carcinoma of the colon or rectum appears to be increasing. Although certain dietary habits appear to be associated with disease incidence, the putative carcinogens in the lumen of the bowel remain unidentified. The use of clinical screening based on a combination of proctosigmoidoscopy and tests for occult fecal blood allows detection of colorectal carcinomas at an early stage; however, it is unclear whether such screening is cost-effective in persons over 40 years of age or if treatment undertaken on the basis of screening results truly alters the natural history of the disease. Surgical resection is the mainstay of curative therapy, and its effectiveness will probably be enhanced by adjuvant x-ray therapy and chemotherapy.",
author = "David Soybel and Bliss, {David P.} and Wells, {Samuel A.}",
year = "1987",
month = "1",
day = "1",
doi = "10.1016/S0147-0272(87)80005-3",
language = "English (US)",
volume = "9",
pages = "259--356",
journal = "Current Problems in Cancer",
issn = "0147-0272",
publisher = "Mosby Inc.",
number = "5",

}

Colon and rectal carcinoma. / Soybel, David; Bliss, David P.; Wells, Samuel A.

In: Current Problems in Cancer, Vol. 9, No. 5, 01.01.1987, p. 259-356.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Colon and rectal carcinoma

AU - Soybel, David

AU - Bliss, David P.

AU - Wells, Samuel A.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - In the United States the incidence of carcinoma of the colon or rectum appears to be increasing. Although certain dietary habits appear to be associated with disease incidence, the putative carcinogens in the lumen of the bowel remain unidentified. The use of clinical screening based on a combination of proctosigmoidoscopy and tests for occult fecal blood allows detection of colorectal carcinomas at an early stage; however, it is unclear whether such screening is cost-effective in persons over 40 years of age or if treatment undertaken on the basis of screening results truly alters the natural history of the disease. Surgical resection is the mainstay of curative therapy, and its effectiveness will probably be enhanced by adjuvant x-ray therapy and chemotherapy.

AB - In the United States the incidence of carcinoma of the colon or rectum appears to be increasing. Although certain dietary habits appear to be associated with disease incidence, the putative carcinogens in the lumen of the bowel remain unidentified. The use of clinical screening based on a combination of proctosigmoidoscopy and tests for occult fecal blood allows detection of colorectal carcinomas at an early stage; however, it is unclear whether such screening is cost-effective in persons over 40 years of age or if treatment undertaken on the basis of screening results truly alters the natural history of the disease. Surgical resection is the mainstay of curative therapy, and its effectiveness will probably be enhanced by adjuvant x-ray therapy and chemotherapy.

UR - http://www.scopus.com/inward/record.url?scp=0023409574&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023409574&partnerID=8YFLogxK

U2 - 10.1016/S0147-0272(87)80005-3

DO - 10.1016/S0147-0272(87)80005-3

M3 - Article

C2 - 3319428

AN - SCOPUS:0023409574

VL - 9

SP - 259

EP - 356

JO - Current Problems in Cancer

JF - Current Problems in Cancer

SN - 0147-0272

IS - 5

ER -