Color-Doppler- directed echocardiographic technique for the evaluation of left ventricular diastolic filling

Validation by radionuclide angiography

J. F. Ren, Mark Tulchinsky, K. Chandrasekaran, J. J. Ross, R. V. Foley, D. G. Karalis, R. S. Pennock, W. S. Frankl

Research output: Contribution to journalArticle

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Abstract

A novel color-Doppler-directed echocardiographic technique was developed for the determination of left ventricular (LV) peak filling rate normalized to the end-diastolic volume (NPFR). To calculate this diastolic filling index, the mitral valve cross-sectional area (MVA) was measured using color Doppler inflow column width for guidance, and the LV volumes were determined by biplane Simpson's rule. For comparison, NPFR was measured in a similar fashion by a non-color Doppler echocardiographic (DE) technique with MVA determined on the gray scale image. Radionuclide angiography (RNA) was used as a reference standard. Thirty-two patients were considered for this study. Seven were excluded because of technical (5 cases) or pathophysiological reasons. The mean NPFR values for color DE, non-color DE and RNA were 2.14 ± 1.03, 2.83 ± 1.43 and 2.08 ± 1.43 s-1, respectively. There was a fair correlation demonstrated between the non-color DE method and RNA (r= 0.60, SEE = 1.18 s-1. On the other hand, an excellent correlation existed between the color DE method and RNA (r = 0.85, SEE = 0.55 s(-1). This improvement was statistically significant (p < 0.05). In conclusion, the color DE method for determination of NPFR is more reliable than the non-color DE method in reproducing RNA results. However, DE techniques are considerably less applicable than RNA, because 22% of the patients successfully tested with RNA could not be studied with DE methods.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalAmerican Journal of Noninvasive Cardiology
Volume7
Issue number1
DOIs
StatePublished - Jan 1 1993

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Radionuclide Angiography
Color
Mitral Valve

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Ren, J. F. ; Tulchinsky, Mark ; Chandrasekaran, K. ; Ross, J. J. ; Foley, R. V. ; Karalis, D. G. ; Pennock, R. S. ; Frankl, W. S. / Color-Doppler- directed echocardiographic technique for the evaluation of left ventricular diastolic filling : Validation by radionuclide angiography. In: American Journal of Noninvasive Cardiology. 1993 ; Vol. 7, No. 1. pp. 1-6.
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abstract = "A novel color-Doppler-directed echocardiographic technique was developed for the determination of left ventricular (LV) peak filling rate normalized to the end-diastolic volume (NPFR). To calculate this diastolic filling index, the mitral valve cross-sectional area (MVA) was measured using color Doppler inflow column width for guidance, and the LV volumes were determined by biplane Simpson's rule. For comparison, NPFR was measured in a similar fashion by a non-color Doppler echocardiographic (DE) technique with MVA determined on the gray scale image. Radionuclide angiography (RNA) was used as a reference standard. Thirty-two patients were considered for this study. Seven were excluded because of technical (5 cases) or pathophysiological reasons. The mean NPFR values for color DE, non-color DE and RNA were 2.14 ± 1.03, 2.83 ± 1.43 and 2.08 ± 1.43 s-1, respectively. There was a fair correlation demonstrated between the non-color DE method and RNA (r= 0.60, SEE = 1.18 s-1. On the other hand, an excellent correlation existed between the color DE method and RNA (r = 0.85, SEE = 0.55 s(-1). This improvement was statistically significant (p < 0.05). In conclusion, the color DE method for determination of NPFR is more reliable than the non-color DE method in reproducing RNA results. However, DE techniques are considerably less applicable than RNA, because 22{\%} of the patients successfully tested with RNA could not be studied with DE methods.",
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Color-Doppler- directed echocardiographic technique for the evaluation of left ventricular diastolic filling : Validation by radionuclide angiography. / Ren, J. F.; Tulchinsky, Mark; Chandrasekaran, K.; Ross, J. J.; Foley, R. V.; Karalis, D. G.; Pennock, R. S.; Frankl, W. S.

In: American Journal of Noninvasive Cardiology, Vol. 7, No. 1, 01.01.1993, p. 1-6.

Research output: Contribution to journalArticle

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AU - Ren, J. F.

AU - Tulchinsky, Mark

AU - Chandrasekaran, K.

AU - Ross, J. J.

AU - Foley, R. V.

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AU - Frankl, W. S.

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