Combined factor V-VIII deficiency: A case report with studies of factor V and VIII activation by thrombin

M. B. Hultin, M. E. Eyster

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations

    Abstract

    A new case of combined factor V-VIII deficiency is reported with in vitro studies of factors V and VIII activation by thrombin. The normal activation of factors V and VIII demonstrated in the patient's plasma and the equivalent levels of factor VIII coagulant activity and coagulant antigen support the hypothesis that a quantitative rather than qualitative defect in factors V and VIII is present in this disorder.

    Original languageEnglish (US)
    Pages (from-to)983-985
    Number of pages3
    JournalBlood
    Volume58
    Issue number5
    DOIs
    StatePublished - 1981

    All Science Journal Classification (ASJC) codes

    • Biochemistry
    • Immunology
    • Hematology
    • Cell Biology

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