Combined factor V-VIII deficiency: A case report with studies of factor V and VIII activation by thrombin

M. B. Hultin, M. E. Eyster

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A new case of combined factor V-VIII deficiency is reported with in vitro studies of factors V and VIII activation by thrombin. The normal activation of factors V and VIII demonstrated in the patient's plasma and the equivalent levels of factor VIII coagulant activity and coagulant antigen support the hypothesis that a quantitative rather than qualitative defect in factors V and VIII is present in this disorder.

Original languageEnglish (US)
Pages (from-to)983-985
Number of pages3
JournalBlood
Volume58
Issue number5
StatePublished - 1981

Fingerprint

Factor V Deficiency
Factor V
Factor VIII
Hemophilia A
Thrombin
Chemical activation
Coagulants
Plasmas
Antigens
Defects

All Science Journal Classification (ASJC) codes

  • Hematology

Cite this

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abstract = "A new case of combined factor V-VIII deficiency is reported with in vitro studies of factors V and VIII activation by thrombin. The normal activation of factors V and VIII demonstrated in the patient's plasma and the equivalent levels of factor VIII coagulant activity and coagulant antigen support the hypothesis that a quantitative rather than qualitative defect in factors V and VIII is present in this disorder.",
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Combined factor V-VIII deficiency : A case report with studies of factor V and VIII activation by thrombin. / Hultin, M. B.; Eyster, M. E.

In: Blood, Vol. 58, No. 5, 1981, p. 983-985.

Research output: Contribution to journalArticle

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AB - A new case of combined factor V-VIII deficiency is reported with in vitro studies of factors V and VIII activation by thrombin. The normal activation of factors V and VIII demonstrated in the patient's plasma and the equivalent levels of factor VIII coagulant activity and coagulant antigen support the hypothesis that a quantitative rather than qualitative defect in factors V and VIII is present in this disorder.

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