TY - JOUR
T1 - Comparing salt appetites
T2 - Induction with intracranial hormones or dietary sodium restriction
AU - Prakash, Madhavi R.
AU - Norgren, Ralph
PY - 1991
Y1 - 1991
N2 - To raise a natural sodium appetite in the laboratory requires approximately 10 days on a very low sodium diet. Most other regimens induce sodium appetite more rapidly, but also result in behavioral or physiological changes not observed in the deprivation-induced state. We compared the characteristics of need-free sodium appetite induced either by systemic aldosterone combined with an intracerebroventricular (ICV) injection of angiotensin II or by a single ICV injection of renin with an appetite induced by 10 days of sodium deprivation. We measured the latency to drink water and 3% NaCl, as well as the amount of these fluids consumed at 30 min, 3 h, and 24 h. Angiotensin induced the shortest latency for both water and salt drinking, but the overall salt intake was lower. In 24 h, renin and sodium deprivation both induced about 14 ml of NaCl consumption, but the time course of the fluid intake differed for the two regimens.
AB - To raise a natural sodium appetite in the laboratory requires approximately 10 days on a very low sodium diet. Most other regimens induce sodium appetite more rapidly, but also result in behavioral or physiological changes not observed in the deprivation-induced state. We compared the characteristics of need-free sodium appetite induced either by systemic aldosterone combined with an intracerebroventricular (ICV) injection of angiotensin II or by a single ICV injection of renin with an appetite induced by 10 days of sodium deprivation. We measured the latency to drink water and 3% NaCl, as well as the amount of these fluids consumed at 30 min, 3 h, and 24 h. Angiotensin induced the shortest latency for both water and salt drinking, but the overall salt intake was lower. In 24 h, renin and sodium deprivation both induced about 14 ml of NaCl consumption, but the time course of the fluid intake differed for the two regimens.
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U2 - 10.1016/0361-9230(91)90132-4
DO - 10.1016/0361-9230(91)90132-4
M3 - Article
C2 - 1959037
AN - SCOPUS:0025989691
VL - 27
SP - 397
EP - 401
JO - Journal of Electrophysiological Techniques
JF - Journal of Electrophysiological Techniques
SN - 0361-9230
IS - 3-4
ER -