Comparison of factor VIII levels after adrenalin in classic hemophilia and von Willebrand's disease (vWd)

M. E. Eyster, James Ballard, D. Prager

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The factor VIII response to adrenalin was compared in 5 patients with von Willebrand's disease (vWd) and 10 hemophiliacs with baseline factor VIII procoagulant activity (VIII AHF) of 0.01 u/ml or greater. Patients with vWd showed a two-fold VIII AHF increase, while those with hemophilia showed no significant change 1 hr following the subcutaneous injection of adrenalin. These results suggest that the adrenalin stimulation test may be of value in distinguishing certain patients with mild hemophilia from those with vWd.

Original languageEnglish (US)
Pages (from-to)657-662
Number of pages6
JournalThrombosis and Haemostasis
Volume39
Issue number3
DOIs
StatePublished - Jan 1 1978

All Science Journal Classification (ASJC) codes

  • Hematology

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