Comparison of factor VIII levels after adrenalin in classic hemophilia and von Willebrand's disease (vWd)

M. E. Eyster, James Ballard, D. Prager

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The factor VIII response to adrenalin was compared in 5 patients with von Willebrand's disease (vWd) and 10 hemophiliacs with baseline factor VIII procoagulant activity (VIII AHF) of 0.01 u/ml or greater. Patients with vWd showed a two-fold VIII AHF increase, while those with hemophilia showed no significant change 1 hr following the subcutaneous injection of adrenalin. These results suggest that the adrenalin stimulation test may be of value in distinguishing certain patients with mild hemophilia from those with vWd.

Original languageEnglish (US)
Pages (from-to)657-662
Number of pages6
JournalThrombosis and Haemostasis
Volume39
Issue number3
StatePublished - 1978

Fingerprint

von Willebrand Diseases
Factor VIII
Hemophilia A
Epinephrine
Subcutaneous Injections

All Science Journal Classification (ASJC) codes

  • Hematology

Cite this

@article{9e688b3838704f0b954952ecbb6d8714,
title = "Comparison of factor VIII levels after adrenalin in classic hemophilia and von Willebrand's disease (vWd)",
abstract = "The factor VIII response to adrenalin was compared in 5 patients with von Willebrand's disease (vWd) and 10 hemophiliacs with baseline factor VIII procoagulant activity (VIII AHF) of 0.01 u/ml or greater. Patients with vWd showed a two-fold VIII AHF increase, while those with hemophilia showed no significant change 1 hr following the subcutaneous injection of adrenalin. These results suggest that the adrenalin stimulation test may be of value in distinguishing certain patients with mild hemophilia from those with vWd.",
author = "Eyster, {M. E.} and James Ballard and D. Prager",
year = "1978",
language = "English (US)",
volume = "39",
pages = "657--662",
journal = "Thrombosis and Haemostasis",
issn = "0340-6245",
publisher = "Schattauer GmbH",
number = "3",

}

Comparison of factor VIII levels after adrenalin in classic hemophilia and von Willebrand's disease (vWd). / Eyster, M. E.; Ballard, James; Prager, D.

In: Thrombosis and Haemostasis, Vol. 39, No. 3, 1978, p. 657-662.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparison of factor VIII levels after adrenalin in classic hemophilia and von Willebrand's disease (vWd)

AU - Eyster, M. E.

AU - Ballard, James

AU - Prager, D.

PY - 1978

Y1 - 1978

N2 - The factor VIII response to adrenalin was compared in 5 patients with von Willebrand's disease (vWd) and 10 hemophiliacs with baseline factor VIII procoagulant activity (VIII AHF) of 0.01 u/ml or greater. Patients with vWd showed a two-fold VIII AHF increase, while those with hemophilia showed no significant change 1 hr following the subcutaneous injection of adrenalin. These results suggest that the adrenalin stimulation test may be of value in distinguishing certain patients with mild hemophilia from those with vWd.

AB - The factor VIII response to adrenalin was compared in 5 patients with von Willebrand's disease (vWd) and 10 hemophiliacs with baseline factor VIII procoagulant activity (VIII AHF) of 0.01 u/ml or greater. Patients with vWd showed a two-fold VIII AHF increase, while those with hemophilia showed no significant change 1 hr following the subcutaneous injection of adrenalin. These results suggest that the adrenalin stimulation test may be of value in distinguishing certain patients with mild hemophilia from those with vWd.

UR - http://www.scopus.com/inward/record.url?scp=0018127253&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018127253&partnerID=8YFLogxK

M3 - Article

C2 - 309190

AN - SCOPUS:0018127253

VL - 39

SP - 657

EP - 662

JO - Thrombosis and Haemostasis

JF - Thrombosis and Haemostasis

SN - 0340-6245

IS - 3

ER -