Comparison of mandibular phenotypic and genetic integration between baboon and mouse

Katherine E. Willmore, Charles C. Roseman, Jeffrey Rogers, James M. Cheverud, Joan Therese Richtsmeier

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

In this study we compare patterns of mandibular integration between mice and baboons using both phenotypic and quantitative genetic data. Specifically, we test how well each species fits with the mosaic model of mandibular integration suggested by Atchley and Hall (Biol Rev Camb Philos Soc 66:101-157, 1991) based on developmental modules. We hypothesize that patterns of integration will be similar for mice and baboons and that both species will show strong integration within developmental modules and weaker integration between modules. Corresponding landmark data were collected from the hemi-mandibles of an advanced intercross mouse sample (N = 1239) and mandibles from a baboon sample of known pedigree from the Southwest Foundation for Biomedical Research (N = 430). We used four methods of analysis to quantify and compare the degree of mandibular integration between species including two methods based on a priori assumptions, and two a posteriori analyses. We found that patterns of integration are broadly similar for baboon and mouse mandibles, with both species displaying a modular pattern of integration. While there is a general trend of similarity in integration patterns between species, there were some marked differences. Mice are strongly correlated among distances within the coronoid process and the incisive alveolar region, whereas baboons are strongly integrated within the condylar process. We discuss the potential evolutionary implications of the similar patterns of integration between these species with an emphasis on the role of modularity.

Original languageEnglish (US)
Pages (from-to)19-36
Number of pages18
JournalEvolutionary Biology
Volume36
Issue number1
DOIs
StatePublished - Mar 1 2009

Fingerprint

Papio
mice
biomedical research
quantitative genetics
pedigree
comparison
sampling
methodology
testing

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics

Cite this

Willmore, Katherine E. ; Roseman, Charles C. ; Rogers, Jeffrey ; Cheverud, James M. ; Richtsmeier, Joan Therese. / Comparison of mandibular phenotypic and genetic integration between baboon and mouse. In: Evolutionary Biology. 2009 ; Vol. 36, No. 1. pp. 19-36.
@article{8ebe2ecaf6ab4f3eb885c58549de1a62,
title = "Comparison of mandibular phenotypic and genetic integration between baboon and mouse",
abstract = "In this study we compare patterns of mandibular integration between mice and baboons using both phenotypic and quantitative genetic data. Specifically, we test how well each species fits with the mosaic model of mandibular integration suggested by Atchley and Hall (Biol Rev Camb Philos Soc 66:101-157, 1991) based on developmental modules. We hypothesize that patterns of integration will be similar for mice and baboons and that both species will show strong integration within developmental modules and weaker integration between modules. Corresponding landmark data were collected from the hemi-mandibles of an advanced intercross mouse sample (N = 1239) and mandibles from a baboon sample of known pedigree from the Southwest Foundation for Biomedical Research (N = 430). We used four methods of analysis to quantify and compare the degree of mandibular integration between species including two methods based on a priori assumptions, and two a posteriori analyses. We found that patterns of integration are broadly similar for baboon and mouse mandibles, with both species displaying a modular pattern of integration. While there is a general trend of similarity in integration patterns between species, there were some marked differences. Mice are strongly correlated among distances within the coronoid process and the incisive alveolar region, whereas baboons are strongly integrated within the condylar process. We discuss the potential evolutionary implications of the similar patterns of integration between these species with an emphasis on the role of modularity.",
author = "Willmore, {Katherine E.} and Roseman, {Charles C.} and Jeffrey Rogers and Cheverud, {James M.} and Richtsmeier, {Joan Therese}",
year = "2009",
month = "3",
day = "1",
doi = "10.1007/s11692-009-9056-9",
language = "English (US)",
volume = "36",
pages = "19--36",
journal = "Evolutionary Biology",
issn = "0071-3260",
publisher = "Springer Verlag",
number = "1",

}

Comparison of mandibular phenotypic and genetic integration between baboon and mouse. / Willmore, Katherine E.; Roseman, Charles C.; Rogers, Jeffrey; Cheverud, James M.; Richtsmeier, Joan Therese.

In: Evolutionary Biology, Vol. 36, No. 1, 01.03.2009, p. 19-36.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparison of mandibular phenotypic and genetic integration between baboon and mouse

AU - Willmore, Katherine E.

AU - Roseman, Charles C.

AU - Rogers, Jeffrey

AU - Cheverud, James M.

AU - Richtsmeier, Joan Therese

PY - 2009/3/1

Y1 - 2009/3/1

N2 - In this study we compare patterns of mandibular integration between mice and baboons using both phenotypic and quantitative genetic data. Specifically, we test how well each species fits with the mosaic model of mandibular integration suggested by Atchley and Hall (Biol Rev Camb Philos Soc 66:101-157, 1991) based on developmental modules. We hypothesize that patterns of integration will be similar for mice and baboons and that both species will show strong integration within developmental modules and weaker integration between modules. Corresponding landmark data were collected from the hemi-mandibles of an advanced intercross mouse sample (N = 1239) and mandibles from a baboon sample of known pedigree from the Southwest Foundation for Biomedical Research (N = 430). We used four methods of analysis to quantify and compare the degree of mandibular integration between species including two methods based on a priori assumptions, and two a posteriori analyses. We found that patterns of integration are broadly similar for baboon and mouse mandibles, with both species displaying a modular pattern of integration. While there is a general trend of similarity in integration patterns between species, there were some marked differences. Mice are strongly correlated among distances within the coronoid process and the incisive alveolar region, whereas baboons are strongly integrated within the condylar process. We discuss the potential evolutionary implications of the similar patterns of integration between these species with an emphasis on the role of modularity.

AB - In this study we compare patterns of mandibular integration between mice and baboons using both phenotypic and quantitative genetic data. Specifically, we test how well each species fits with the mosaic model of mandibular integration suggested by Atchley and Hall (Biol Rev Camb Philos Soc 66:101-157, 1991) based on developmental modules. We hypothesize that patterns of integration will be similar for mice and baboons and that both species will show strong integration within developmental modules and weaker integration between modules. Corresponding landmark data were collected from the hemi-mandibles of an advanced intercross mouse sample (N = 1239) and mandibles from a baboon sample of known pedigree from the Southwest Foundation for Biomedical Research (N = 430). We used four methods of analysis to quantify and compare the degree of mandibular integration between species including two methods based on a priori assumptions, and two a posteriori analyses. We found that patterns of integration are broadly similar for baboon and mouse mandibles, with both species displaying a modular pattern of integration. While there is a general trend of similarity in integration patterns between species, there were some marked differences. Mice are strongly correlated among distances within the coronoid process and the incisive alveolar region, whereas baboons are strongly integrated within the condylar process. We discuss the potential evolutionary implications of the similar patterns of integration between these species with an emphasis on the role of modularity.

UR - http://www.scopus.com/inward/record.url?scp=69849109638&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=69849109638&partnerID=8YFLogxK

U2 - 10.1007/s11692-009-9056-9

DO - 10.1007/s11692-009-9056-9

M3 - Article

AN - SCOPUS:69849109638

VL - 36

SP - 19

EP - 36

JO - Evolutionary Biology

JF - Evolutionary Biology

SN - 0071-3260

IS - 1

ER -