Abstract
Background The combination of peripheral neuropathy and other treatment-associated side effects is likely related to an increased incidence of falls in cancer survivors. The purpose of this study was to quantify differences in postural stability between healthy age-matched controls and cancer survivors. Methods Quiet standing under four conditions (eyes open/closed, rigid/compliant surface) was assessed in 34 cancer survivors (2 males, 32 females; age: 54(13) yrs., height: 1.62(0.07) m; mass: 78.5(19.5) kg) and 34 age-matched controls (5 males, 29 females; age: 54(15) yrs.; height: 1.62(0.08) m; mass: 72.8(21.1) kg). Center of pressure data were collected for 30 s and the trajectories were analyzed (100 Hz). Three-factor (group*surface*vision) mixed model MANOVAs with repeated measures were used to determine the effect of vision and surface on postural steadiness between groups. Findings Cancer survivors exhibited larger mediolateral root-mean square distance and velocity of the center of pressure, as well as increased 95% confidence ellipse area (P < 0.01) when compared with their age-matched counterparts. For example, when removing visual input, cancer survivors had an average increase in 95% confidence ellipse area of 91.8 mm2 while standing on a rigid surface compared to a 68.6 mm2 increase for the control group. No frequency-based center of pressure measures differed between groups. Interpretation Cancer survivors exhibit decreased postural steadiness when compared with age-matched controls. For cancer survivors undergoing rehabilitation focused on existing balance deficits, a small subset of the center of pressure measures presented here can be used to track progress throughout the intervention and potentially mitigate fall risk.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-6 |
| Number of pages | 6 |
| Journal | Clinical Biomechanics |
| Volume | 50 |
| DOIs | |
| State | Published - Dec 1 2017 |
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All Science Journal Classification (ASJC) codes
- Biophysics
- Orthopedics and Sports Medicine
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Comparison of posture and balance in cancer survivors and age-matched controls. / Schmitt, Abigail C.; Repka, Chris P.; Heise, Gary D.; Challis, John Henry; Smith, Jeremy D.
In: Clinical Biomechanics, Vol. 50, 01.12.2017, p. 1-6.Research output: Contribution to journal › Article
TY - JOUR
T1 - Comparison of posture and balance in cancer survivors and age-matched controls
AU - Schmitt, Abigail C.
AU - Repka, Chris P.
AU - Heise, Gary D.
AU - Challis, John Henry
AU - Smith, Jeremy D.
PY - 2017/12/1
Y1 - 2017/12/1
N2 - Background The combination of peripheral neuropathy and other treatment-associated side effects is likely related to an increased incidence of falls in cancer survivors. The purpose of this study was to quantify differences in postural stability between healthy age-matched controls and cancer survivors. Methods Quiet standing under four conditions (eyes open/closed, rigid/compliant surface) was assessed in 34 cancer survivors (2 males, 32 females; age: 54(13) yrs., height: 1.62(0.07) m; mass: 78.5(19.5) kg) and 34 age-matched controls (5 males, 29 females; age: 54(15) yrs.; height: 1.62(0.08) m; mass: 72.8(21.1) kg). Center of pressure data were collected for 30 s and the trajectories were analyzed (100 Hz). Three-factor (group*surface*vision) mixed model MANOVAs with repeated measures were used to determine the effect of vision and surface on postural steadiness between groups. Findings Cancer survivors exhibited larger mediolateral root-mean square distance and velocity of the center of pressure, as well as increased 95% confidence ellipse area (P < 0.01) when compared with their age-matched counterparts. For example, when removing visual input, cancer survivors had an average increase in 95% confidence ellipse area of 91.8 mm2 while standing on a rigid surface compared to a 68.6 mm2 increase for the control group. No frequency-based center of pressure measures differed between groups. Interpretation Cancer survivors exhibit decreased postural steadiness when compared with age-matched controls. For cancer survivors undergoing rehabilitation focused on existing balance deficits, a small subset of the center of pressure measures presented here can be used to track progress throughout the intervention and potentially mitigate fall risk.
AB - Background The combination of peripheral neuropathy and other treatment-associated side effects is likely related to an increased incidence of falls in cancer survivors. The purpose of this study was to quantify differences in postural stability between healthy age-matched controls and cancer survivors. Methods Quiet standing under four conditions (eyes open/closed, rigid/compliant surface) was assessed in 34 cancer survivors (2 males, 32 females; age: 54(13) yrs., height: 1.62(0.07) m; mass: 78.5(19.5) kg) and 34 age-matched controls (5 males, 29 females; age: 54(15) yrs.; height: 1.62(0.08) m; mass: 72.8(21.1) kg). Center of pressure data were collected for 30 s and the trajectories were analyzed (100 Hz). Three-factor (group*surface*vision) mixed model MANOVAs with repeated measures were used to determine the effect of vision and surface on postural steadiness between groups. Findings Cancer survivors exhibited larger mediolateral root-mean square distance and velocity of the center of pressure, as well as increased 95% confidence ellipse area (P < 0.01) when compared with their age-matched counterparts. For example, when removing visual input, cancer survivors had an average increase in 95% confidence ellipse area of 91.8 mm2 while standing on a rigid surface compared to a 68.6 mm2 increase for the control group. No frequency-based center of pressure measures differed between groups. Interpretation Cancer survivors exhibit decreased postural steadiness when compared with age-matched controls. For cancer survivors undergoing rehabilitation focused on existing balance deficits, a small subset of the center of pressure measures presented here can be used to track progress throughout the intervention and potentially mitigate fall risk.
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U2 - 10.1016/j.clinbiomech.2017.09.010
DO - 10.1016/j.clinbiomech.2017.09.010
M3 - Article
C2 - 28968535
AN - SCOPUS:85030184592
VL - 50
SP - 1
EP - 6
JO - Clinical Biomechanics
JF - Clinical Biomechanics
SN - 0268-0033
ER -